Clinical assessment of axis I psychiatric morbidity in chronic epilepsy: A multicenter investigation

Jana E. Jones, Brace P. Hermann, John J. Barry, Frank Gilliam, Andres M Kanner, Kimford J. Meador

Research output: Contribution to journalArticlepeer-review


This study characterizes the rate of current Axis I DSM-IV disorders using a brief standardized psychiatric interview procedure, the Mini International Neuropsychiatric Interview (v5.0) (MINI), and determined the validity of MINI diagnoses of current depressive episodes to the research standard (Structured Clinical Interview for DSM-IV Disorders [SCID]). One hundred seventy-four patients with chronic epilepsy from five tertiary medical centers were interviewed using the MINI and the mood disorders module of the SCID. Current Axis I disorders were evident in one-half the sample (49%), with prevalent anxiety (30.4%) and mood (21.8%) disorders. Major depressive episode was the most common individual diagnosis (17.2%). Concordance was high between the MINI and SCID for diagnoses of current depression, especially for major depression. Of those with current major depression, less than one-half were treated with antidepressant medications. Current Axis I DSM-IV diagnoses can be effectively and accurately identified in clinical settings using shorter standardized psychiatric interview techniques. Issues regarding recognition and treatment of psychiatric morbidity in epilepsy are discussed. copyright

Original languageEnglish (US)
Pages (from-to)172-179
Number of pages8
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Issue number2
StatePublished - Mar 2005
Externally publishedYes

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Neuroscience(all)


Dive into the research topics of 'Clinical assessment of axis I psychiatric morbidity in chronic epilepsy: A multicenter investigation'. Together they form a unique fingerprint.

Cite this