Clinical and epidemiological characteristics of individuals with very high rapid plasma reagin

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The objective of the study was to identify clinical and epidemiological characteristics of patients with infectious syphilis who presented with a high rapid plasma reagin (RPR) titre (≥1: 512) during the year of 2009 at the Miami Dade County Health Department (MDCHD) STD clinic. Potential cases were identified by a search in the electronic database. Among 519 individuals identified with reactive RPR, 190 individuals met criteria for infectious syphilis and 32 of them had at least one RPR titre of ≥1: 512. We found that the majority of individuals with high RPR were men who have sex with men (82%), from ethnic minorities (91%), and HIV infected (75%) but only 3 of them were on antiretroviral therapy. Overall, 50% of these patients with very high RPR titres were symptomatic, and the most common symptom was skin rash (93%).

Original languageEnglish (US)
Pages (from-to)593-595
Number of pages3
JournalInternational Journal of STD and AIDS
Issue number8
StatePublished - Jul 2014



  • AIDS
  • high RPR
  • HIV
  • MSM
  • rapid plasma reagin
  • sexually transmitted infection
  • Syphilis
  • Treponema pallidum

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Pharmacology (medical)
  • Infectious Diseases

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