Circadian and day-to-day variation of prostatic acid phosphatase

I. Nissenkorn, D. D. Mickey, D. B. Miller, M. S. Soloway

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Abstract

The circadian and day-to-day variation of serum levels of prostatic acid phosphatase determined by radioimmunoassay was investigated in 10 men with a normal prostate, 8 with benign prostatic hyperplasia and 10 with prostate cancer. Serum samples were obtained on 1 day at 8 a.m., 12:00 noon and 4:30 p.m. in 23 patients, and on 3 consecutive days at 8 a.m. in an additional 5 patients. There was a variability in enzyme level throughout the day but without any distinct pattern. Prostate cancer patients with elevated levels of prostatic acid phosphatase did demonstrate a greater variability throughout the day than patients with a normal prostate or with benign prostatic hyperplasia. The day-to-day serum prostatic acid phosphatase in patients with a normal prostate varied little and remained within the normal range.

Original languageEnglish (US)
Pages (from-to)1122-1123
Number of pages2
JournalJournal of Urology
Volume127
Issue number6
StatePublished - Jan 1 1982

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ASJC Scopus subject areas

  • Urology

Cite this

Nissenkorn, I., Mickey, D. D., Miller, D. B., & Soloway, M. S. (1982). Circadian and day-to-day variation of prostatic acid phosphatase. Journal of Urology, 127(6), 1122-1123.