Cine MR in the evaluation of normal and abnormal CSF flow: intracranial and intraspinal studies

Robert Quencer, M. Judith Post, R. S. Hinks

Research output: Contribution to journalArticle

167 Citations (Scopus)

Abstract

Evaluation of intracranial and intraspinal CSF flow was accomplished by the use of cardiac gated gradient echo magnetic resonance (MR) technique. Normal patterns of pulsatile flow within the ventricles, cisterns and cervical subarachnoid space were established by this technique and these observations were compared to prior description of CSF flow. With systole there is downward (caudal) flow of CSF in the aqueduct of Sylvius, the foramen of Magendie, the basal cisterns and the dorsal and ventral subarachnoid spaces while during diastole, upward (cranial) flow of CSF in these same structures is seen. The relationships between the cardiac cycle and the CSF pulsations are demonstrated on both magnitude reconstruction and phase reconstruction MR images. Calculations of actual fluid velocity within CSF containing spaces can be obtained from the phase reconstruction images and holds promise for a more accurate analysis of CSF flow. In conditions which result in alterations of flow, cine MR dramatically shows either obstruction or excessively turbulent flow within the CSF pathways. The site of obstructed flow whether in the third ventricle, aqueduct, fourth ventricle, or subarachnoid space can be appreciated by changes in or absence of the normal hypointense signal. Cystic cord lesions such as congenital syringohydromyelia and posttraumatic spinal cord cysts may show pulsatile flow of CSF, a fact which can relate to progressive enlargement of these cysts. The distinction between myelomalacia and cyst formation in the cord is facilitated by the technique. Although the use of cine MR for the analysis of CSF flow is in its infancy, our experience indicates that this technique is useful in a wide range of pathological conditions including, but not limited to, conditions resulting in hydrocephalus or cystic cord lesions.

Original languageEnglish
Pages (from-to)371-391
Number of pages21
JournalNeuroradiology
Volume32
Issue number5
DOIs
StatePublished - Sep 1 1990

Fingerprint

Subarachnoid Space
Magnetic Resonance Spectroscopy
Cysts
Pulsatile Flow
Cerebral Aqueduct
Fourth Ventricle
Third Ventricle
Diastole
Computer-Assisted Image Processing
Systole
Hydrocephalus
Spinal Cord

Keywords

  • Cerebrospinal fluid flow
  • Cine-MR
  • Hydrocephalus
  • Magnetic resonance imaging
  • Spinal cord cyst

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

Cite this

Cine MR in the evaluation of normal and abnormal CSF flow : intracranial and intraspinal studies. / Quencer, Robert; Judith Post, M.; Hinks, R. S.

In: Neuroradiology, Vol. 32, No. 5, 01.09.1990, p. 371-391.

Research output: Contribution to journalArticle

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