Ciguatera fish poisoning: Treatment, prevention and management

Melissa A. Friedman, Lora E. Fleming, Mercedes Fernandez, Paul Bienfang, Kathleen Schrank, Robert Dickey, Marie Yasmine Bottein, Lorraine Backer, Ram Ayyar, Richard Weisman, Sharon Watkins, Ray Granade, Andrew Reich

Research output: Contribution to journalReview articlepeer-review

164 Scopus citations

Abstract

Ciguatera Fish Poisoning (CFP) is the most frequently reported seafood-toxin illness in the world, and it causes substantial physical and functional impact. It produces a myriad of gastrointestinal, neurologic and/or cardiovascular symptoms which last days to weeks, or even months. Although there are reports of symptom amelioration with some interventions (e.g. IV mannitol), the appropriate treatment for CFP remains unclear to many physicians. We review the literature on the treatments for CFP, including randomized controlled studies and anecdotal reports. The article is intended to clarify treatment options, and provide information about management and prevention of CFP, for emergency room physicians, poison control information providers, other health care providers, and patients.

Original languageEnglish (US)
Pages (from-to)456-479
Number of pages24
JournalMarine Drugs
Volume6
Issue number3
DOIs
StatePublished - Sep 2008

Keywords

  • Ciguatera fish poisoning
  • Ciguatoxin
  • Harmful algal bloom (HAB)
  • Human health
  • Marine toxins
  • Treatment

ASJC Scopus subject areas

  • Drug Discovery

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