Chronic retinal detachment and neovascular glaucoma after intravitreal stem cell injection for Usher Syndrome

Kay T. Khine, Thomas A. Albini, Richard K. Lee

Research output: Contribution to journalArticle

Abstract

A 42-year-old Hispanic female underwent intravitreal autologous adipose-tissue derived stem cell injection to her left eye in the Dominican Republic for treatment of retinitis pigmentosa associated with Usher Syndrome. Prior to intravitreal injection, the patient's best-corrected-visual-acuity (BCVA) was 1/200. The patient experienced decreased vision gradually over a 3-month period. The patient presented with no light perception (NLP) vision with a total funnel retinal detachment, as well as hyphema, iris neovascularization, and nearly 360 posterior synechiae of the iris to the lens capsule. The patient suffered from ocular pain with an intraocular pressure (IOP) of 37 mm Hg. Transcleral cyclophotocoagulation was performed. The IOP was 6 mm Hg six weeks after treatment and the patient was pain free.

Original languageEnglish (US)
Article number100647
JournalAmerican Journal of Ophthalmology Case Reports
Volume18
DOIs
StatePublished - Jun 2020

Keywords

  • Autologous stem cell transplantation
  • Intravitreal injection of stem cells
  • Neovascular glaucoma
  • Retinitis pigmentosa
  • Stem cells
  • US stem cell clinics
  • Usher syndrome

ASJC Scopus subject areas

  • Ophthalmology

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