Chronic ergot toxicity: A rare cause of lower extremity ischemia

George Garcia, James M. Goff, Neal C. Hadro, Sean D. O'Donnell, Patricia S. Greatorex

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Chronic ergot toxicity is a rare cause of lower extremity ischemia. The cornerstone of therapy in ergot toxicity is to discontinue the use of caffeine, cigarettes, and all ergot-containing medications. Although multiple different therapies have been recommended for acute toxicity, no specific treatment is uniformly recommended in chronic toxicity. We present a case of long-term ergot use for migraine headaches in a woman who had severe chronic lower extremity claudication. This case demonstrates the unique features associated with the diagnosis and management of chronic ergot toxicity. We recommend a conservative approach consisting of observation, antiplatelet agents, and the discontinuance of ergots. If symptoms progress to rest pain or gangrene, surgical treatment should be considered.

Original languageEnglish
Pages (from-to)1245-1247
Number of pages3
JournalJournal of Vascular Surgery
Volume31
Issue number6
DOIs
StatePublished - Jul 11 2000
Externally publishedYes

Fingerprint

Lower Extremity
Ischemia
Gangrene
Platelet Aggregation Inhibitors
Therapeutics
Caffeine
Migraine Disorders
Tobacco Products
Observation
Pain

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Garcia, G., Goff, J. M., Hadro, N. C., O'Donnell, S. D., & Greatorex, P. S. (2000). Chronic ergot toxicity: A rare cause of lower extremity ischemia. Journal of Vascular Surgery, 31(6), 1245-1247. https://doi.org/10.1067/mva.2000.105668

Chronic ergot toxicity : A rare cause of lower extremity ischemia. / Garcia, George; Goff, James M.; Hadro, Neal C.; O'Donnell, Sean D.; Greatorex, Patricia S.

In: Journal of Vascular Surgery, Vol. 31, No. 6, 11.07.2000, p. 1245-1247.

Research output: Contribution to journalArticle

Garcia, G, Goff, JM, Hadro, NC, O'Donnell, SD & Greatorex, PS 2000, 'Chronic ergot toxicity: A rare cause of lower extremity ischemia', Journal of Vascular Surgery, vol. 31, no. 6, pp. 1245-1247. https://doi.org/10.1067/mva.2000.105668
Garcia, George ; Goff, James M. ; Hadro, Neal C. ; O'Donnell, Sean D. ; Greatorex, Patricia S. / Chronic ergot toxicity : A rare cause of lower extremity ischemia. In: Journal of Vascular Surgery. 2000 ; Vol. 31, No. 6. pp. 1245-1247.
@article{e92e265ba01b4c7e83aec40b3a39d049,
title = "Chronic ergot toxicity: A rare cause of lower extremity ischemia",
abstract = "Chronic ergot toxicity is a rare cause of lower extremity ischemia. The cornerstone of therapy in ergot toxicity is to discontinue the use of caffeine, cigarettes, and all ergot-containing medications. Although multiple different therapies have been recommended for acute toxicity, no specific treatment is uniformly recommended in chronic toxicity. We present a case of long-term ergot use for migraine headaches in a woman who had severe chronic lower extremity claudication. This case demonstrates the unique features associated with the diagnosis and management of chronic ergot toxicity. We recommend a conservative approach consisting of observation, antiplatelet agents, and the discontinuance of ergots. If symptoms progress to rest pain or gangrene, surgical treatment should be considered.",
author = "George Garcia and Goff, {James M.} and Hadro, {Neal C.} and O'Donnell, {Sean D.} and Greatorex, {Patricia S.}",
year = "2000",
month = "7",
day = "11",
doi = "10.1067/mva.2000.105668",
language = "English",
volume = "31",
pages = "1245--1247",
journal = "Journal of Vascular Surgery",
issn = "0741-5214",
publisher = "Mosby Inc.",
number = "6",

}

TY - JOUR

T1 - Chronic ergot toxicity

T2 - A rare cause of lower extremity ischemia

AU - Garcia, George

AU - Goff, James M.

AU - Hadro, Neal C.

AU - O'Donnell, Sean D.

AU - Greatorex, Patricia S.

PY - 2000/7/11

Y1 - 2000/7/11

N2 - Chronic ergot toxicity is a rare cause of lower extremity ischemia. The cornerstone of therapy in ergot toxicity is to discontinue the use of caffeine, cigarettes, and all ergot-containing medications. Although multiple different therapies have been recommended for acute toxicity, no specific treatment is uniformly recommended in chronic toxicity. We present a case of long-term ergot use for migraine headaches in a woman who had severe chronic lower extremity claudication. This case demonstrates the unique features associated with the diagnosis and management of chronic ergot toxicity. We recommend a conservative approach consisting of observation, antiplatelet agents, and the discontinuance of ergots. If symptoms progress to rest pain or gangrene, surgical treatment should be considered.

AB - Chronic ergot toxicity is a rare cause of lower extremity ischemia. The cornerstone of therapy in ergot toxicity is to discontinue the use of caffeine, cigarettes, and all ergot-containing medications. Although multiple different therapies have been recommended for acute toxicity, no specific treatment is uniformly recommended in chronic toxicity. We present a case of long-term ergot use for migraine headaches in a woman who had severe chronic lower extremity claudication. This case demonstrates the unique features associated with the diagnosis and management of chronic ergot toxicity. We recommend a conservative approach consisting of observation, antiplatelet agents, and the discontinuance of ergots. If symptoms progress to rest pain or gangrene, surgical treatment should be considered.

UR - http://www.scopus.com/inward/record.url?scp=0033946234&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033946234&partnerID=8YFLogxK

U2 - 10.1067/mva.2000.105668

DO - 10.1067/mva.2000.105668

M3 - Article

C2 - 10842162

AN - SCOPUS:0033946234

VL - 31

SP - 1245

EP - 1247

JO - Journal of Vascular Surgery

JF - Journal of Vascular Surgery

SN - 0741-5214

IS - 6

ER -