Chromosome segregation into the spermatozoa of two men heterozygous for different reciprocal translocations

W. Balkan, R. H. Martin

Research output: Contribution to journalArticle

53 Scopus citations

Abstract

Sperm chromosomes from two human males, each heterozygous for a different reciprocal translocation, were examined. Chromosomally normal sperm were found in equal numbers to those carrying the translocation in the balanced form, in both males. Alternate segregation was more common than adjacent segregation in both translocations. Male W.G. had a greater proportion of sperm containing chromosome abnormalities unrelated to the translocation than did J.S., the second made studied. J.S. however, had a greater frequency of chromosomally unbalanced sperm. The great majority of unbalanced sperm in both males was due to adjacent I segregation.

Original languageEnglish (US)
Pages (from-to)345-348
Number of pages4
JournalHuman Genetics
Volume63
Issue number4
DOIs
StatePublished - Jun 1 1983
Externally publishedYes

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

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