Chromatin remodeling and Rb activity

J. William Harbour, Douglas C. Dean

Research output: Contribution to journalArticle

108 Citations (Scopus)

Abstract

Progression of cells through the cell cycle is central to normal cell proliferation, and checkpoints that regulate this cycle are targets of tumorigenic mutations. One of these checkpoints is the Rb family of proteins that seems to regulate exit of cells from both G1 and S phase of the cell cycle. Recent studies have linked the function of the Rb family to chromatin remodeling enzymes.

Original languageEnglish
Pages (from-to)685-689
Number of pages5
JournalCurrent Opinion in Cell Biology
Volume12
Issue number6
DOIs
StatePublished - Dec 5 2000
Externally publishedYes

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Chromatin Assembly and Disassembly
Cell Cycle
Retinoblastoma Protein
G1 Phase
S Phase
Cell Proliferation
Mutation
Enzymes

ASJC Scopus subject areas

  • Cell Biology

Cite this

Chromatin remodeling and Rb activity. / William Harbour, J.; Dean, Douglas C.

In: Current Opinion in Cell Biology, Vol. 12, No. 6, 05.12.2000, p. 685-689.

Research output: Contribution to journalArticle

William Harbour, J. ; Dean, Douglas C. / Chromatin remodeling and Rb activity. In: Current Opinion in Cell Biology. 2000 ; Vol. 12, No. 6. pp. 685-689.
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