Chondroblastoma-like chondroma of soft tissue: An underrecognized variant and its differential diagnosis

Justin M. Cates, Andrew Rosenberg, John X. O'Connell, G. Petur Nielsen

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Soft-tissue chondromas are usually composed entirely of mature hyaline cartilage. Infrequently, however, they may exhibit morphologic features that result in diagnostic difficulty. The authors report a series of right hypercellular soft-tissue chondromas composed of enlarged chondrocytes within a variable amount of chondroid matrix that often demonstrated delicate calcifications and contained numerous osteoclast-like multinucleated giant cells. This histologic appearance closely resembles that of chondroblastoma of bone. However, its extraosseous location, dense cellularity, and poorly formed cartilage can cause confusion with more aggressive chondroid neoplasms of soft tissue. The clinicopathologic features of these chondroblastoma-like chondromas are discussed, emphasizing the characteristics that facilitate their accurate identification.

Original languageEnglish
Pages (from-to)661-666
Number of pages6
JournalAmerican Journal of Surgical Pathology
Volume25
Issue number5
DOIs
StatePublished - May 21 2001
Externally publishedYes

Fingerprint

Chondroblastoma
Chondroma
Differential Diagnosis
Soft Tissue Neoplasms
Hyaline Cartilage
Osteoclasts
Giant Cells
Chondrocytes
Cartilage
Bone and Bones

Keywords

  • Chondroblastoma
  • Chondroblastoma-like chondroma
  • Soft-tissue chondroma

ASJC Scopus subject areas

  • Anatomy
  • Pathology and Forensic Medicine

Cite this

Chondroblastoma-like chondroma of soft tissue : An underrecognized variant and its differential diagnosis. / Cates, Justin M.; Rosenberg, Andrew; O'Connell, John X.; Nielsen, G. Petur.

In: American Journal of Surgical Pathology, Vol. 25, No. 5, 21.05.2001, p. 661-666.

Research output: Contribution to journalArticle

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