Abstract
Soft-tissue chondromas are usually composed entirely of mature hyaline cartilage. Infrequently, however, they may exhibit morphologic features that result in diagnostic difficulty. The authors report a series of right hypercellular soft-tissue chondromas composed of enlarged chondrocytes within a variable amount of chondroid matrix that often demonstrated delicate calcifications and contained numerous osteoclast-like multinucleated giant cells. This histologic appearance closely resembles that of chondroblastoma of bone. However, its extraosseous location, dense cellularity, and poorly formed cartilage can cause confusion with more aggressive chondroid neoplasms of soft tissue. The clinicopathologic features of these chondroblastoma-like chondromas are discussed, emphasizing the characteristics that facilitate their accurate identification.
| Original language | English |
|---|---|
| Pages (from-to) | 661-666 |
| Number of pages | 6 |
| Journal | American Journal of Surgical Pathology |
| Volume | 25 |
| Issue number | 5 |
| DOIs | |
| State | Published - May 21 2001 |
| Externally published | Yes |
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Keywords
- Chondroblastoma
- Chondroblastoma-like chondroma
- Soft-tissue chondroma
ASJC Scopus subject areas
- Anatomy
- Pathology and Forensic Medicine
Cite this
Chondroblastoma-like chondroma of soft tissue : An underrecognized variant and its differential diagnosis. / Cates, Justin M.; Rosenberg, Andrew; O'Connell, John X.; Nielsen, G. Petur.
In: American Journal of Surgical Pathology, Vol. 25, No. 5, 21.05.2001, p. 661-666.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Chondroblastoma-like chondroma of soft tissue
T2 - An underrecognized variant and its differential diagnosis
AU - Cates, Justin M.
AU - Rosenberg, Andrew
AU - O'Connell, John X.
AU - Nielsen, G. Petur
PY - 2001/5/21
Y1 - 2001/5/21
N2 - Soft-tissue chondromas are usually composed entirely of mature hyaline cartilage. Infrequently, however, they may exhibit morphologic features that result in diagnostic difficulty. The authors report a series of right hypercellular soft-tissue chondromas composed of enlarged chondrocytes within a variable amount of chondroid matrix that often demonstrated delicate calcifications and contained numerous osteoclast-like multinucleated giant cells. This histologic appearance closely resembles that of chondroblastoma of bone. However, its extraosseous location, dense cellularity, and poorly formed cartilage can cause confusion with more aggressive chondroid neoplasms of soft tissue. The clinicopathologic features of these chondroblastoma-like chondromas are discussed, emphasizing the characteristics that facilitate their accurate identification.
AB - Soft-tissue chondromas are usually composed entirely of mature hyaline cartilage. Infrequently, however, they may exhibit morphologic features that result in diagnostic difficulty. The authors report a series of right hypercellular soft-tissue chondromas composed of enlarged chondrocytes within a variable amount of chondroid matrix that often demonstrated delicate calcifications and contained numerous osteoclast-like multinucleated giant cells. This histologic appearance closely resembles that of chondroblastoma of bone. However, its extraosseous location, dense cellularity, and poorly formed cartilage can cause confusion with more aggressive chondroid neoplasms of soft tissue. The clinicopathologic features of these chondroblastoma-like chondromas are discussed, emphasizing the characteristics that facilitate their accurate identification.
KW - Chondroblastoma
KW - Chondroblastoma-like chondroma
KW - Soft-tissue chondroma
UR - http://www.scopus.com/inward/record.url?scp=0035002585&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035002585&partnerID=8YFLogxK
U2 - 10.1097/00000478-200105000-00015
DO - 10.1097/00000478-200105000-00015
M3 - Article
C2 - 11342780
AN - SCOPUS:0035002585
VL - 25
SP - 661
EP - 666
JO - American Journal of Surgical Pathology
JF - American Journal of Surgical Pathology
SN - 0147-5185
IS - 5
ER -