Cholinergic projections from the parabigeminal nucleus (Ch8) to the superior colliculus in the mouse: a combined analysis of horseradish peroxidase transport and choline acetyltransferase immunohistochemistry

E. J. Mufson, T. L. Martin, Deborah C Mash, B. H. Wainer, M. M. Mesulam

Research output: Contribution to journalArticle

124 Citations (Scopus)

Abstract

Choline acetyltransferase (ChAT) immunocytochemistry, acetylcholinesterase histochemistry and muscarinic receptor autoradiography demonstrated a cholinergic innervation within the superior colliculus. A method for the concurrent visualization of ChAT and transported horseradish peroxidase showed that a major extrinsic source for this cholinergic input is in the parabigeminal nucleus. We have designated these cholinergic neurons as the Ch8 cell group.

Original languageEnglish
Pages (from-to)144-148
Number of pages5
JournalBrain Research
Volume370
Issue number1
DOIs
StatePublished - Apr 2 1986
Externally publishedYes

Fingerprint

Choline O-Acetyltransferase
Superior Colliculi
Horseradish Peroxidase
Cholinergic Agents
Immunohistochemistry
Cholinergic Neurons
Muscarinic Receptors
Acetylcholinesterase
Autoradiography

Keywords

  • choline acetyltransferase
  • cholinergic
  • horseradish peroxidase
  • immunohistochemistry
  • mouse
  • superior coliculus

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Cholinergic projections from the parabigeminal nucleus (Ch8) to the superior colliculus in the mouse : a combined analysis of horseradish peroxidase transport and choline acetyltransferase immunohistochemistry. / Mufson, E. J.; Martin, T. L.; Mash, Deborah C; Wainer, B. H.; Mesulam, M. M.

In: Brain Research, Vol. 370, No. 1, 02.04.1986, p. 144-148.

Research output: Contribution to journalArticle

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