Cholinergic projections from the parabigeminal nucleus (Ch8) to the superior colliculus in the mouse: a combined analysis of horseradish peroxidase transport and choline acetyltransferase immunohistochemistry

E. J. Mufson, T. L. Martin, D. C. Mash, B. H. Wainer, M. M. Mesulam

Research output: Contribution to journalArticle

125 Scopus citations

Abstract

Choline acetyltransferase (ChAT) immunocytochemistry, acetylcholinesterase histochemistry and muscarinic receptor autoradiography demonstrated a cholinergic innervation within the superior colliculus. A method for the concurrent visualization of ChAT and transported horseradish peroxidase showed that a major extrinsic source for this cholinergic input is in the parabigeminal nucleus. We have designated these cholinergic neurons as the Ch8 cell group.

Original languageEnglish (US)
Pages (from-to)144-148
Number of pages5
JournalBrain Research
Volume370
Issue number1
DOIs
StatePublished - Apr 2 1986

Keywords

  • choline acetyltransferase
  • cholinergic
  • horseradish peroxidase
  • immunohistochemistry
  • mouse
  • superior coliculus

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

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