Chimerism and liver transplant tolerance

Davide Mineo, Camillo Ricordi

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Chimerism and tolerance in a recipient of a deceased-donor liver transplant. Alexander SI, Smith N, Hu M, Verran D, Shun A, Dorney S, Smith A, Webster B, Shaw PJ, Lammi A, Stormon MO. Complete hematopoietic chimerism and tolerance of a liver allograft from a deceased male donor developed in a 9-year-old girl, with no evidence of graft-versus-host disease 17 months after transplantation. The tolerance was preceded by a period of severe hemolysis, reflecting partial chimerism that was refractory to standard therapies. The hemolysis resolved after the gradual withdrawal of all immunosuppressive therapy. [Abstract reproduced by permission of N Engl J Med 2008;358:369-374].

Original languageEnglish
Pages (from-to)478-480
Number of pages3
JournalJournal of Hepatology
Volume49
Issue number3
DOIs
StatePublished - Sep 1 2008

Fingerprint

Chimerism
Hemolysis
Transplants
Liver
Tissue Donors
Graft vs Host Disease
Immunosuppressive Agents
Allografts
Transplantation
Therapeutics

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Chimerism and liver transplant tolerance. / Mineo, Davide; Ricordi, Camillo.

In: Journal of Hepatology, Vol. 49, No. 3, 01.09.2008, p. 478-480.

Research output: Contribution to journalArticle

Mineo, Davide ; Ricordi, Camillo. / Chimerism and liver transplant tolerance. In: Journal of Hepatology. 2008 ; Vol. 49, No. 3. pp. 478-480.
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