Chimerism and liver transplant tolerance

Davide Mineo, Camillo Ricordi

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Chimerism and tolerance in a recipient of a deceased-donor liver transplant. Alexander SI, Smith N, Hu M, Verran D, Shun A, Dorney S, Smith A, Webster B, Shaw PJ, Lammi A, Stormon MO. Complete hematopoietic chimerism and tolerance of a liver allograft from a deceased male donor developed in a 9-year-old girl, with no evidence of graft-versus-host disease 17 months after transplantation. The tolerance was preceded by a period of severe hemolysis, reflecting partial chimerism that was refractory to standard therapies. The hemolysis resolved after the gradual withdrawal of all immunosuppressive therapy. [Abstract reproduced by permission of N Engl J Med 2008;358:369-374].

Original languageEnglish (US)
Pages (from-to)478-480
Number of pages3
JournalJournal of Hepatology
Volume49
Issue number3
DOIs
StatePublished - Sep 1 2008

ASJC Scopus subject areas

  • Hepatology

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