Childhood malignant melanoma. Incidence and etiology

J. L. Bader, F. P. Li, P. M. Olmstead, N. A. Strickman, D. M. Green

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

Etiology of malignant melanoma in persons younger than 20 years of age was examined using data from two sources: 1) medical records of 78 patients with this diagnosis at six hospitals, and 2) information on 101 individuals included in 10 U.S. population-based SEER cancer registry areas between 1973-1976. Annual melanoma incidence rate was 3.4 per million in boys, 3.9 per million in girls, and 10-fold greater in white children than in black children. Melanoma was seven times more frequent in the second decade of life than the first. Skin was the primary site of melanoma in approximately 90% of the children in the two study series. The predominant cutaneous sites were head, neck, and trunk among boys, and arms and legs among girls. These variations by age, race, and sex suggest the etiologic role of cumulative skin exposure to sunlight, particularly in two patients with xeroderma pigmentosum. In 14 patients in the hospital series, melanoma was report to develop within pigmented nevi that were present at birth.

Original languageEnglish
Pages (from-to)341-345
Number of pages5
JournalAmerican Journal of Pediatric Hematology/Oncology
Volume7
Issue number4
StatePublished - Dec 1 1985
Externally publishedYes

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Melanoma
Incidence
Skin
Pigmented Nevus
Xeroderma Pigmentosum
Sunlight
Information Storage and Retrieval
Medical Records
Registries
Leg
Arm
Neck
Head
Parturition
Population
Neoplasms

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Oncology
  • Hematology

Cite this

Bader, J. L., Li, F. P., Olmstead, P. M., Strickman, N. A., & Green, D. M. (1985). Childhood malignant melanoma. Incidence and etiology. American Journal of Pediatric Hematology/Oncology, 7(4), 341-345.

Childhood malignant melanoma. Incidence and etiology. / Bader, J. L.; Li, F. P.; Olmstead, P. M.; Strickman, N. A.; Green, D. M.

In: American Journal of Pediatric Hematology/Oncology, Vol. 7, No. 4, 01.12.1985, p. 341-345.

Research output: Contribution to journalArticle

Bader, JL, Li, FP, Olmstead, PM, Strickman, NA & Green, DM 1985, 'Childhood malignant melanoma. Incidence and etiology', American Journal of Pediatric Hematology/Oncology, vol. 7, no. 4, pp. 341-345.
Bader JL, Li FP, Olmstead PM, Strickman NA, Green DM. Childhood malignant melanoma. Incidence and etiology. American Journal of Pediatric Hematology/Oncology. 1985 Dec 1;7(4):341-345.
Bader, J. L. ; Li, F. P. ; Olmstead, P. M. ; Strickman, N. A. ; Green, D. M. / Childhood malignant melanoma. Incidence and etiology. In: American Journal of Pediatric Hematology/Oncology. 1985 ; Vol. 7, No. 4. pp. 341-345.
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