Abstract
A 2 1/2 -month-old female infant presented with multiple tense bullae on the hands and feet. Analysis of biopsy specimens confirmed our clinical impression of childhood bullous pemphigoid. Confirmatory data included type IV collagen mapping of the basement membrane zone, a readily available technique that helps distinguish childhood bullous pemphigoid from childhood epidermolysis bullosa acquisita. To our knowledge, our patient is the youngest described with childhood bullous pemphigoid, and we use this opportunity to review the literature and examine the clinical and immunologic features, treatment, and prognosis of this rare childhood immunobullous disorder.
| Original language | English |
|---|---|
| Pages (from-to) | 378-386 |
| Number of pages | 9 |
| Journal | Archives of Dermatology |
| Volume | 127 |
| Issue number | 3 |
| DOIs | |
| State | Published - Apr 3 1991 |
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ASJC Scopus subject areas
- Dermatology
Cite this
Childhood bullous pemphigoid. Clinical and immunologic features, treatment, and prognosis. / Nemeth, A. J.; Klein, A. D.; Gould, E. W.; Schachner, Lawrence A.
In: Archives of Dermatology, Vol. 127, No. 3, 03.04.1991, p. 378-386.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Childhood bullous pemphigoid. Clinical and immunologic features, treatment, and prognosis
AU - Nemeth, A. J.
AU - Klein, A. D.
AU - Gould, E. W.
AU - Schachner, Lawrence A
PY - 1991/4/3
Y1 - 1991/4/3
N2 - A 2 1/2 -month-old female infant presented with multiple tense bullae on the hands and feet. Analysis of biopsy specimens confirmed our clinical impression of childhood bullous pemphigoid. Confirmatory data included type IV collagen mapping of the basement membrane zone, a readily available technique that helps distinguish childhood bullous pemphigoid from childhood epidermolysis bullosa acquisita. To our knowledge, our patient is the youngest described with childhood bullous pemphigoid, and we use this opportunity to review the literature and examine the clinical and immunologic features, treatment, and prognosis of this rare childhood immunobullous disorder.
AB - A 2 1/2 -month-old female infant presented with multiple tense bullae on the hands and feet. Analysis of biopsy specimens confirmed our clinical impression of childhood bullous pemphigoid. Confirmatory data included type IV collagen mapping of the basement membrane zone, a readily available technique that helps distinguish childhood bullous pemphigoid from childhood epidermolysis bullosa acquisita. To our knowledge, our patient is the youngest described with childhood bullous pemphigoid, and we use this opportunity to review the literature and examine the clinical and immunologic features, treatment, and prognosis of this rare childhood immunobullous disorder.
UR - http://www.scopus.com/inward/record.url?scp=0026065166&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026065166&partnerID=8YFLogxK
U2 - 10.1001/archderm.127.3.378
DO - 10.1001/archderm.127.3.378
M3 - Article
C2 - 1998369
AN - SCOPUS:0026065166
VL - 127
SP - 378
EP - 386
JO - JAMA Dermatology
JF - JAMA Dermatology
SN - 2168-6068
IS - 3
ER -