Chicken gizzard

Relation between calcium-activated phosphorylation and contraction

P. E. Hoar, W. Glenn Kerrick, P. S. Cassidy

Research output: Contribution to journalArticle

96 Citations (Scopus)

Abstract

Of the proteins in mechanically disrupted chicken gizzard fibers (no functional sarcolemma) only the 20,000-dalton light chains of myosin underwent large (a2+- and Sr2+-dependent changes in phosphorylation. Phosphorylation closely corresponded with the Ca2+- and Sr2+-activated tensions. Adnosine 5'-O (3'- thiotriphosphate) only in the presence of Ca2+ induced irreversible Ca2+-insensitive activation of tension and thiophosphorylation of the 20,000-dalton light chains, and blocked incorporation of 32P from [γ-32P]adenosine triphosphate into the myosin light chains.

Original languageEnglish
Pages (from-to)503-506
Number of pages4
JournalScience
Volume204
Issue number4392
StatePublished - Jan 1 1979
Externally publishedYes

Fingerprint

Avian Gizzard
Myosin Light Chains
Chickens
Phosphorylation
Calcium
Sarcolemma
Adenosine Triphosphate
Light
Proteins

ASJC Scopus subject areas

  • General

Cite this

Chicken gizzard : Relation between calcium-activated phosphorylation and contraction. / Hoar, P. E.; Kerrick, W. Glenn; Cassidy, P. S.

In: Science, Vol. 204, No. 4392, 01.01.1979, p. 503-506.

Research output: Contribution to journalArticle

Hoar, P. E. ; Kerrick, W. Glenn ; Cassidy, P. S. / Chicken gizzard : Relation between calcium-activated phosphorylation and contraction. In: Science. 1979 ; Vol. 204, No. 4392. pp. 503-506.
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