Chiari I malformations and syringomyelia

Ramin J. Javahery, Steven Vanni, Allan D.O. Levi

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


The pathogenesis of the Chiari I malformation (CMI) as well as its associated syringomyelic cavity remains relatively vague despite significant recent advances. Multiple theories have been proposed to explain both the origin of the CMI and the development of a syrinx. This article fleshes out the major theories for both of these conditions. The indeterminate quality of this condition can also be seen in its presentation. There are myriad documented presenting signs and symptoms in patients with CMI. The major clinical syndromes and most common signs and symptoms are reviewed. Most importantly for both patient and physician, this lack of consensus extends to treatment. Because of historical unsatisfying surgical results, a multitude of treatment options have been and are currently being proposed for the treatment of both conditions. The major schools of thought with regard to treatment are also reviewed.

Original languageEnglish (US)
Pages (from-to)119-130
Number of pages12
JournalSeminars in Neurosurgery
Issue number2
StatePublished - Jan 1 2002


  • Chiari malformation
  • Syringomyelia
  • Syrinx

ASJC Scopus subject areas

  • Clinical Neurology


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