Chiari I malformations and syringomyelia

Ramin J. Javahery, Steven Vanni, Allan D Levi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The pathogenesis of the Chiari I malformation (CMI) as well as its associated syringomyelic cavity remains relatively vague despite significant recent advances. Multiple theories have been proposed to explain both the origin of the CMI and the development of a syrinx. This article fleshes out the major theories for both of these conditions. The indeterminate quality of this condition can also be seen in its presentation. There are myriad documented presenting signs and symptoms in patients with CMI. The major clinical syndromes and most common signs and symptoms are reviewed. Most importantly for both patient and physician, this lack of consensus extends to treatment. Because of historical unsatisfying surgical results, a multitude of treatment options have been and are currently being proposed for the treatment of both conditions. The major schools of thought with regard to treatment are also reviewed.

Original languageEnglish
Pages (from-to)119-130
Number of pages12
JournalSeminars in Neurosurgery
Volume13
Issue number2
DOIs
StatePublished - Jan 1 2002

Fingerprint

Syringomyelia
Signs and Symptoms
Syringes
Therapeutics
Physicians

Keywords

  • Chiari malformation
  • Syringomyelia
  • Syrinx

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Chiari I malformations and syringomyelia. / Javahery, Ramin J.; Vanni, Steven; Levi, Allan D.

In: Seminars in Neurosurgery, Vol. 13, No. 2, 01.01.2002, p. 119-130.

Research output: Contribution to journalArticle

Javahery, Ramin J. ; Vanni, Steven ; Levi, Allan D. / Chiari I malformations and syringomyelia. In: Seminars in Neurosurgery. 2002 ; Vol. 13, No. 2. pp. 119-130.
@article{86fb4871d3ad4a8997a89344b170743b,
title = "Chiari I malformations and syringomyelia",
abstract = "The pathogenesis of the Chiari I malformation (CMI) as well as its associated syringomyelic cavity remains relatively vague despite significant recent advances. Multiple theories have been proposed to explain both the origin of the CMI and the development of a syrinx. This article fleshes out the major theories for both of these conditions. The indeterminate quality of this condition can also be seen in its presentation. There are myriad documented presenting signs and symptoms in patients with CMI. The major clinical syndromes and most common signs and symptoms are reviewed. Most importantly for both patient and physician, this lack of consensus extends to treatment. Because of historical unsatisfying surgical results, a multitude of treatment options have been and are currently being proposed for the treatment of both conditions. The major schools of thought with regard to treatment are also reviewed.",
keywords = "Chiari malformation, Syringomyelia, Syrinx",
author = "Javahery, {Ramin J.} and Steven Vanni and Levi, {Allan D}",
year = "2002",
month = "1",
day = "1",
doi = "10.1055/s-2002-35809",
language = "English",
volume = "13",
pages = "119--130",
journal = "Seminars in Neurosurgery",
issn = "1526-8012",
publisher = "Thieme Medical Publishers",
number = "2",

}

TY - JOUR

T1 - Chiari I malformations and syringomyelia

AU - Javahery, Ramin J.

AU - Vanni, Steven

AU - Levi, Allan D

PY - 2002/1/1

Y1 - 2002/1/1

N2 - The pathogenesis of the Chiari I malformation (CMI) as well as its associated syringomyelic cavity remains relatively vague despite significant recent advances. Multiple theories have been proposed to explain both the origin of the CMI and the development of a syrinx. This article fleshes out the major theories for both of these conditions. The indeterminate quality of this condition can also be seen in its presentation. There are myriad documented presenting signs and symptoms in patients with CMI. The major clinical syndromes and most common signs and symptoms are reviewed. Most importantly for both patient and physician, this lack of consensus extends to treatment. Because of historical unsatisfying surgical results, a multitude of treatment options have been and are currently being proposed for the treatment of both conditions. The major schools of thought with regard to treatment are also reviewed.

AB - The pathogenesis of the Chiari I malformation (CMI) as well as its associated syringomyelic cavity remains relatively vague despite significant recent advances. Multiple theories have been proposed to explain both the origin of the CMI and the development of a syrinx. This article fleshes out the major theories for both of these conditions. The indeterminate quality of this condition can also be seen in its presentation. There are myriad documented presenting signs and symptoms in patients with CMI. The major clinical syndromes and most common signs and symptoms are reviewed. Most importantly for both patient and physician, this lack of consensus extends to treatment. Because of historical unsatisfying surgical results, a multitude of treatment options have been and are currently being proposed for the treatment of both conditions. The major schools of thought with regard to treatment are also reviewed.

KW - Chiari malformation

KW - Syringomyelia

KW - Syrinx

UR - http://www.scopus.com/inward/record.url?scp=0036446595&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036446595&partnerID=8YFLogxK

U2 - 10.1055/s-2002-35809

DO - 10.1055/s-2002-35809

M3 - Article

AN - SCOPUS:0036446595

VL - 13

SP - 119

EP - 130

JO - Seminars in Neurosurgery

JF - Seminars in Neurosurgery

SN - 1526-8012

IS - 2

ER -