Chemotherapy of the transplantable adenocarcinoma (R-3327) of the copenhagen rat

N. L. Block, F. Camuzzi, J. Denefrio, M. Troner, A. Claflin, B. Stover, V. A. Politano

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


A number of therapeutic agents including L-asparaginase, Actinomycin-D, CCNV, Hydroxyurea, 5-FU, Cis-platinum, Cyclophosphamide, orchiectomy, Adriamycin and DES alone and in various combinations has been applied against the Dunning R-3327 rat prostatic adenocarcinoma subline G. The authors found a parallel between the results of this study and those of similar therapeutic application to the human tumor. The authors concluded that this animal model may prove to be a useful screening system for agents against human prostatic cancer.

Original languageEnglish (US)
Pages (from-to)110-113
Number of pages4
JournalOncology (Switzerland)
Issue number3
StatePublished - 1977
Externally publishedYes


  • Chemotherapy-Prostate-Adenocarcinoma-Tumor model

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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