The application of chemotherapy to testicular cancer is briefly reviewed. Chlorambucil is the drug of choice for seminoma. It should be combined with dactinomycin when other elements besides seminoma are found. When the tumor is of nonseminomatous histology, the drug combination of 5 FU, cyclophosphamide, methotrexate and vincristine is preferred as the first choice of therapy. Prophylactic chemotherapy in patients with no evidence of tumor after node dissection seems useful at this time. The toxicities of the various chemotherapeutic drugs were briefly discussed. The hazard is nowhere near as great as that of metastatic testicular cancer.
|Original language||English (US)|
|Number of pages||4|
|Journal||Journal of the Florida Medical Association|
|State||Published - Dec 1 1974|
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