Chemonucleolysis with discase; technique, results, case reports

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

This report details observations made while the author was developing personal experience with a method for intradiscal injections in the lumbar spine using chymopapain, in preparation for participation in a subsequent double blind study. Thirty patients were injected with the enzyme according to a standardized protocol, which included discography. All patients were candidates for surgery for disc displacement. The overall rate of satisfactory symptomatic relief was 70% at an average follow up time of 11 months, and 21 of 30 patients returned to their previous employment.

Original languageEnglish
Pages (from-to)115-120
Number of pages6
JournalSpine
Volume1
Issue number2
StatePublished - Dec 1 1976

Fingerprint

Intervertebral Disc Chemolysis
Chymopapain
Double-Blind Method
Spine
Injections
Enzymes

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Orthopedics and Sports Medicine

Cite this

Chemonucleolysis with discase; technique, results, case reports. / Brown, Mark.

In: Spine, Vol. 1, No. 2, 01.12.1976, p. 115-120.

Research output: Contribution to journalArticle

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