Characterizing sleep in children with autism spectrum disorders: A multidimensional approach

Beth A. Malow, Mary L. Marzec, Susan G. McGrew, Lily Wang, Lynnette M. Henderson, Wendy L. Stone

Research output: Contribution to journalArticle

205 Citations (Scopus)

Abstract

Study Objectives: To relate parentally reported sleep concerns in autism spectrum disorders (ASD) to polysomnographic (PSG) findings and measures of daytime behavior and autism symptomatology. Design: Cross-sectional study involving validated questionnaires, sleep histories and diaries, 2 nights of PSG, and the Autism Diagnostic Observation Schedule (ADOS). Setting: Vanderbilt University General Clinical Research Center Sleep Core Participants: 21 children with ASD and 10 typically developing (TD) children, aged 4-10 years. Children were free of psychotropic medications, with no history of mental retardation or epileptic seizures. Interventions: N/A Measurements and Results: Children with ASD were defined as "good sleepers" (10 children) and "poor sleepers" (11 children) on the basis of parental report; the age-comparable TD children were all reported by their parents to be good sleepers. Poor sleepers with ASD showed prolonged sleep latency and decreased sleep efficiency on night 1 of PSG and differed on insomnia-related subscales of the Children's Sleep Habits Questionnaire (CSHQ; increased sleep onset delay and decreased sleep duration). The good sleepers with ASD did not differ from the TD children in sleep architecture or on CSHQ domains. As compared with ASD good sleepers, the ASD poor sleepers also had higher scores related to affective problems on the Child Behavior Checklist and more problems with reciprocal social interaction on the ADOS. Conclusions: Parentally reported sleep concerns of insomnia in children with ASD are substantiated by validated sleep questionnaires and by PSG. Furthermore, good sleepers with ASD showed fewer affective problems and better social interactions than ASD poor sleepers.

Original languageEnglish (US)
Pages (from-to)1563-1571
Number of pages9
JournalSleep
Volume29
Issue number12
DOIs
StatePublished - Dec 1 2006
Externally publishedYes

Fingerprint

Sleep
Autistic Disorder
Sleep Initiation and Maintenance Disorders
Interpersonal Relations
Appointments and Schedules
Autism Spectrum Disorder
Observation
Child Behavior
Checklist
Intellectual Disability
Habits
Epilepsy
Cross-Sectional Studies
Parents
Research

Keywords

  • Autism Diagnostic Observation Schedule
  • Child Behavior Checklist
  • Children's Sleep Habits Questionnaire
  • Insomnia
  • Polysomnography

ASJC Scopus subject areas

  • Clinical Neurology
  • Physiology (medical)

Cite this

Malow, B. A., Marzec, M. L., McGrew, S. G., Wang, L., Henderson, L. M., & Stone, W. L. (2006). Characterizing sleep in children with autism spectrum disorders: A multidimensional approach. Sleep, 29(12), 1563-1571. https://doi.org/10.1093/sleep/29.12.1563

Characterizing sleep in children with autism spectrum disorders : A multidimensional approach. / Malow, Beth A.; Marzec, Mary L.; McGrew, Susan G.; Wang, Lily; Henderson, Lynnette M.; Stone, Wendy L.

In: Sleep, Vol. 29, No. 12, 01.12.2006, p. 1563-1571.

Research output: Contribution to journalArticle

Malow, BA, Marzec, ML, McGrew, SG, Wang, L, Henderson, LM & Stone, WL 2006, 'Characterizing sleep in children with autism spectrum disorders: A multidimensional approach', Sleep, vol. 29, no. 12, pp. 1563-1571. https://doi.org/10.1093/sleep/29.12.1563
Malow, Beth A. ; Marzec, Mary L. ; McGrew, Susan G. ; Wang, Lily ; Henderson, Lynnette M. ; Stone, Wendy L. / Characterizing sleep in children with autism spectrum disorders : A multidimensional approach. In: Sleep. 2006 ; Vol. 29, No. 12. pp. 1563-1571.
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