Abstract
Purpose: To study the characteristics and outcomes of choroidal neovascularization (CNV) developing after surgery for idiopathic macular holes. Methods: Retrospective, noncomparative case series. Search of diagnostic and procedure databases of four participating institutes identified nine eyes of eight patients with CNV after surgery for idiopathic macular hole. Demographic, clinical, and fundus fluorescein angiographic data were abstracted from patients' medical records. Results: Choroidal neovascularization developed 6 weeks to 30 months after macular hole surgery. The macular hole was closed in all cases. The CNV complex involved the foveal region in 9 (100%) eyes, was predominantly classic in 8 (89%) eyes, and was associated with moderate to severe leakage of fluorescein in 8 (89%) eyes. The CNV was crescent-shaped and spared the central area of retinal pigment epithelial mottling that corresponded to the site of the macular hole in 6 (67%) cases. Other fluorescein angiographic features included retinal pigment epitheliopathy in 6 (67%) eyes and presence of drusen in 7 (78%) eyes. The final visual acuity after a mean follow-up period of 11.2 months (range, 3-16 months) was 20/50 to 20/80 in 2 (22%) eyes, 20/100 to 20/200 in 1 (11 %) eye, and less than 20/200 in 6 (67%) eyes. Conclusion: Choroidal neovascular complexes occurring after macular hole surgery tend to share certain characteristics, including foveal involvement, frequent sparing of the central area corresponding to the site of the closed macular hole, and generally poor visual outcomes. Therapeutic modalities including photodynamic therapy and surgical options may be considered in these patients.
| Original language | English |
|---|---|
| Pages (from-to) | 714-720 |
| Number of pages | 7 |
| Journal | Retina |
| Volume | 24 |
| Issue number | 5 |
| DOIs | |
| State | Published - Oct 1 2004 |
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Keywords
- Age-related macular degeneration
- Choroidal neovascularization
- Macular hole surgery
- Retinal pigment epitheliopathy
ASJC Scopus subject areas
- Ophthalmology
- Sensory Systems
Cite this
Characteristics and outcomes of choroidal neovascularization occurring after macular hole surgery. / Tabandeh, Homayoun; Smiddy, William E; Sullivan, Paul M.; Monshizadeh, Ramin; Rafiei, Nastaran; Cheng, Lingyun; Freeman, William.
In: Retina, Vol. 24, No. 5, 01.10.2004, p. 714-720.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Characteristics and outcomes of choroidal neovascularization occurring after macular hole surgery
AU - Tabandeh, Homayoun
AU - Smiddy, William E
AU - Sullivan, Paul M.
AU - Monshizadeh, Ramin
AU - Rafiei, Nastaran
AU - Cheng, Lingyun
AU - Freeman, William
PY - 2004/10/1
Y1 - 2004/10/1
N2 - Purpose: To study the characteristics and outcomes of choroidal neovascularization (CNV) developing after surgery for idiopathic macular holes. Methods: Retrospective, noncomparative case series. Search of diagnostic and procedure databases of four participating institutes identified nine eyes of eight patients with CNV after surgery for idiopathic macular hole. Demographic, clinical, and fundus fluorescein angiographic data were abstracted from patients' medical records. Results: Choroidal neovascularization developed 6 weeks to 30 months after macular hole surgery. The macular hole was closed in all cases. The CNV complex involved the foveal region in 9 (100%) eyes, was predominantly classic in 8 (89%) eyes, and was associated with moderate to severe leakage of fluorescein in 8 (89%) eyes. The CNV was crescent-shaped and spared the central area of retinal pigment epithelial mottling that corresponded to the site of the macular hole in 6 (67%) cases. Other fluorescein angiographic features included retinal pigment epitheliopathy in 6 (67%) eyes and presence of drusen in 7 (78%) eyes. The final visual acuity after a mean follow-up period of 11.2 months (range, 3-16 months) was 20/50 to 20/80 in 2 (22%) eyes, 20/100 to 20/200 in 1 (11 %) eye, and less than 20/200 in 6 (67%) eyes. Conclusion: Choroidal neovascular complexes occurring after macular hole surgery tend to share certain characteristics, including foveal involvement, frequent sparing of the central area corresponding to the site of the closed macular hole, and generally poor visual outcomes. Therapeutic modalities including photodynamic therapy and surgical options may be considered in these patients.
AB - Purpose: To study the characteristics and outcomes of choroidal neovascularization (CNV) developing after surgery for idiopathic macular holes. Methods: Retrospective, noncomparative case series. Search of diagnostic and procedure databases of four participating institutes identified nine eyes of eight patients with CNV after surgery for idiopathic macular hole. Demographic, clinical, and fundus fluorescein angiographic data were abstracted from patients' medical records. Results: Choroidal neovascularization developed 6 weeks to 30 months after macular hole surgery. The macular hole was closed in all cases. The CNV complex involved the foveal region in 9 (100%) eyes, was predominantly classic in 8 (89%) eyes, and was associated with moderate to severe leakage of fluorescein in 8 (89%) eyes. The CNV was crescent-shaped and spared the central area of retinal pigment epithelial mottling that corresponded to the site of the macular hole in 6 (67%) cases. Other fluorescein angiographic features included retinal pigment epitheliopathy in 6 (67%) eyes and presence of drusen in 7 (78%) eyes. The final visual acuity after a mean follow-up period of 11.2 months (range, 3-16 months) was 20/50 to 20/80 in 2 (22%) eyes, 20/100 to 20/200 in 1 (11 %) eye, and less than 20/200 in 6 (67%) eyes. Conclusion: Choroidal neovascular complexes occurring after macular hole surgery tend to share certain characteristics, including foveal involvement, frequent sparing of the central area corresponding to the site of the closed macular hole, and generally poor visual outcomes. Therapeutic modalities including photodynamic therapy and surgical options may be considered in these patients.
KW - Age-related macular degeneration
KW - Choroidal neovascularization
KW - Macular hole surgery
KW - Retinal pigment epitheliopathy
UR - http://www.scopus.com/inward/record.url?scp=6344221304&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=6344221304&partnerID=8YFLogxK
U2 - 10.1097/00006982-200410000-00005
DO - 10.1097/00006982-200410000-00005
M3 - Article
C2 - 15492624
AN - SCOPUS:6344221304
VL - 24
SP - 714
EP - 720
JO - Retina
JF - Retina
SN - 0275-004X
IS - 5
ER -