Characteristics and outcomes of choroidal neovascularization occurring after macular hole surgery

Homayoun Tabandeh, William E Smiddy, Paul M. Sullivan, Ramin Monshizadeh, Nastaran Rafiei, Lingyun Cheng, William Freeman

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Purpose: To study the characteristics and outcomes of choroidal neovascularization (CNV) developing after surgery for idiopathic macular holes. Methods: Retrospective, noncomparative case series. Search of diagnostic and procedure databases of four participating institutes identified nine eyes of eight patients with CNV after surgery for idiopathic macular hole. Demographic, clinical, and fundus fluorescein angiographic data were abstracted from patients' medical records. Results: Choroidal neovascularization developed 6 weeks to 30 months after macular hole surgery. The macular hole was closed in all cases. The CNV complex involved the foveal region in 9 (100%) eyes, was predominantly classic in 8 (89%) eyes, and was associated with moderate to severe leakage of fluorescein in 8 (89%) eyes. The CNV was crescent-shaped and spared the central area of retinal pigment epithelial mottling that corresponded to the site of the macular hole in 6 (67%) cases. Other fluorescein angiographic features included retinal pigment epitheliopathy in 6 (67%) eyes and presence of drusen in 7 (78%) eyes. The final visual acuity after a mean follow-up period of 11.2 months (range, 3-16 months) was 20/50 to 20/80 in 2 (22%) eyes, 20/100 to 20/200 in 1 (11 %) eye, and less than 20/200 in 6 (67%) eyes. Conclusion: Choroidal neovascular complexes occurring after macular hole surgery tend to share certain characteristics, including foveal involvement, frequent sparing of the central area corresponding to the site of the closed macular hole, and generally poor visual outcomes. Therapeutic modalities including photodynamic therapy and surgical options may be considered in these patients.

Original languageEnglish
Pages (from-to)714-720
Number of pages7
JournalRetina
Volume24
Issue number5
DOIs
StatePublished - Oct 1 2004

Fingerprint

Choroidal Neovascularization
Retinal Perforations
Fluorescein
Retinal Pigments
Photochemotherapy
Visual Acuity
Medical Records
Demography
Outcome Assessment (Health Care)
Databases

Keywords

  • Age-related macular degeneration
  • Choroidal neovascularization
  • Macular hole surgery
  • Retinal pigment epitheliopathy

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems

Cite this

Tabandeh, H., Smiddy, W. E., Sullivan, P. M., Monshizadeh, R., Rafiei, N., Cheng, L., & Freeman, W. (2004). Characteristics and outcomes of choroidal neovascularization occurring after macular hole surgery. Retina, 24(5), 714-720. https://doi.org/10.1097/00006982-200410000-00005

Characteristics and outcomes of choroidal neovascularization occurring after macular hole surgery. / Tabandeh, Homayoun; Smiddy, William E; Sullivan, Paul M.; Monshizadeh, Ramin; Rafiei, Nastaran; Cheng, Lingyun; Freeman, William.

In: Retina, Vol. 24, No. 5, 01.10.2004, p. 714-720.

Research output: Contribution to journalArticle

Tabandeh, H, Smiddy, WE, Sullivan, PM, Monshizadeh, R, Rafiei, N, Cheng, L & Freeman, W 2004, 'Characteristics and outcomes of choroidal neovascularization occurring after macular hole surgery', Retina, vol. 24, no. 5, pp. 714-720. https://doi.org/10.1097/00006982-200410000-00005
Tabandeh, Homayoun ; Smiddy, William E ; Sullivan, Paul M. ; Monshizadeh, Ramin ; Rafiei, Nastaran ; Cheng, Lingyun ; Freeman, William. / Characteristics and outcomes of choroidal neovascularization occurring after macular hole surgery. In: Retina. 2004 ; Vol. 24, No. 5. pp. 714-720.
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abstract = "Purpose: To study the characteristics and outcomes of choroidal neovascularization (CNV) developing after surgery for idiopathic macular holes. Methods: Retrospective, noncomparative case series. Search of diagnostic and procedure databases of four participating institutes identified nine eyes of eight patients with CNV after surgery for idiopathic macular hole. Demographic, clinical, and fundus fluorescein angiographic data were abstracted from patients' medical records. Results: Choroidal neovascularization developed 6 weeks to 30 months after macular hole surgery. The macular hole was closed in all cases. The CNV complex involved the foveal region in 9 (100{\%}) eyes, was predominantly classic in 8 (89{\%}) eyes, and was associated with moderate to severe leakage of fluorescein in 8 (89{\%}) eyes. The CNV was crescent-shaped and spared the central area of retinal pigment epithelial mottling that corresponded to the site of the macular hole in 6 (67{\%}) cases. Other fluorescein angiographic features included retinal pigment epitheliopathy in 6 (67{\%}) eyes and presence of drusen in 7 (78{\%}) eyes. The final visual acuity after a mean follow-up period of 11.2 months (range, 3-16 months) was 20/50 to 20/80 in 2 (22{\%}) eyes, 20/100 to 20/200 in 1 (11 {\%}) eye, and less than 20/200 in 6 (67{\%}) eyes. Conclusion: Choroidal neovascular complexes occurring after macular hole surgery tend to share certain characteristics, including foveal involvement, frequent sparing of the central area corresponding to the site of the closed macular hole, and generally poor visual outcomes. Therapeutic modalities including photodynamic therapy and surgical options may be considered in these patients.",
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AU - Cheng, Lingyun

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N2 - Purpose: To study the characteristics and outcomes of choroidal neovascularization (CNV) developing after surgery for idiopathic macular holes. Methods: Retrospective, noncomparative case series. Search of diagnostic and procedure databases of four participating institutes identified nine eyes of eight patients with CNV after surgery for idiopathic macular hole. Demographic, clinical, and fundus fluorescein angiographic data were abstracted from patients' medical records. Results: Choroidal neovascularization developed 6 weeks to 30 months after macular hole surgery. The macular hole was closed in all cases. The CNV complex involved the foveal region in 9 (100%) eyes, was predominantly classic in 8 (89%) eyes, and was associated with moderate to severe leakage of fluorescein in 8 (89%) eyes. The CNV was crescent-shaped and spared the central area of retinal pigment epithelial mottling that corresponded to the site of the macular hole in 6 (67%) cases. Other fluorescein angiographic features included retinal pigment epitheliopathy in 6 (67%) eyes and presence of drusen in 7 (78%) eyes. The final visual acuity after a mean follow-up period of 11.2 months (range, 3-16 months) was 20/50 to 20/80 in 2 (22%) eyes, 20/100 to 20/200 in 1 (11 %) eye, and less than 20/200 in 6 (67%) eyes. Conclusion: Choroidal neovascular complexes occurring after macular hole surgery tend to share certain characteristics, including foveal involvement, frequent sparing of the central area corresponding to the site of the closed macular hole, and generally poor visual outcomes. Therapeutic modalities including photodynamic therapy and surgical options may be considered in these patients.

AB - Purpose: To study the characteristics and outcomes of choroidal neovascularization (CNV) developing after surgery for idiopathic macular holes. Methods: Retrospective, noncomparative case series. Search of diagnostic and procedure databases of four participating institutes identified nine eyes of eight patients with CNV after surgery for idiopathic macular hole. Demographic, clinical, and fundus fluorescein angiographic data were abstracted from patients' medical records. Results: Choroidal neovascularization developed 6 weeks to 30 months after macular hole surgery. The macular hole was closed in all cases. The CNV complex involved the foveal region in 9 (100%) eyes, was predominantly classic in 8 (89%) eyes, and was associated with moderate to severe leakage of fluorescein in 8 (89%) eyes. The CNV was crescent-shaped and spared the central area of retinal pigment epithelial mottling that corresponded to the site of the macular hole in 6 (67%) cases. Other fluorescein angiographic features included retinal pigment epitheliopathy in 6 (67%) eyes and presence of drusen in 7 (78%) eyes. The final visual acuity after a mean follow-up period of 11.2 months (range, 3-16 months) was 20/50 to 20/80 in 2 (22%) eyes, 20/100 to 20/200 in 1 (11 %) eye, and less than 20/200 in 6 (67%) eyes. Conclusion: Choroidal neovascular complexes occurring after macular hole surgery tend to share certain characteristics, including foveal involvement, frequent sparing of the central area corresponding to the site of the closed macular hole, and generally poor visual outcomes. Therapeutic modalities including photodynamic therapy and surgical options may be considered in these patients.

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KW - Choroidal neovascularization

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KW - Retinal pigment epitheliopathy

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