Characteristic fluorescence response of (6-hydroxy-2-naphthyl)ethenyl pyridinium dyes with bovine serum albumin

Myung Seok Choi, Ankush Gupta, Jung Hwa Seo, S. Velmathi, James N Wilson, Jong S. Park

Research output: Contribution to journalArticle

Abstract

In this study, we report the efficient identification of proteins using (6-hydroxy-2-naphthyl)ethenyl pyridinium dyes (HNEPs). These dyes exhibited characteristic fluorescence responses, showing enhanced fluorescence with a red shift in the case of bovine serum albumin. The nature of the interaction between the dye and the protein was examined using a combination of various spectroscopic techniques. A time-dependent density functional theory analysis supported the strong environment-dependent fluorescence emission properties of the dyes. The current investigation clearly demonstrates that a selective optical responseHNEPs can find potential usefulness as bio-sensing probes.

Original languageEnglish
Pages (from-to)230-236
Number of pages7
JournalBulletin of the Korean Chemical Society
Volume36
Issue number1
DOIs
StatePublished - Jan 20 2015

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Keywords

  • (6-Hydroxy-2-naphthyl)ethenyl pyridinium dye
  • Bovine serum albumin
  • Protein sensing
  • Stern -Volmer constant
  • Stilbazolium dye

ASJC Scopus subject areas

  • Chemistry(all)

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