Several approaches have been used to develop biomaterials with pharmacologic activity for use in cardiovascular medicine. These approaches depend upon whether the active agent is to be: (i) released slowly from the device; or (ii) retained in bound form indefinitely. The approaches also depend upon whether the pharmacologic activity of the agent is designed to modulate local: (i) coagulation; (ii) platelet function; or (iii) cell function in the vessel.
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Cardiology and Cardiovascular Medicine