Abstract
OBJECTIVE - To test models of unidirectional and bidirectional change between treatment adherence and glycemic control in youth with type 1 diabetes. RESEARCH DESIGN AND METHODS - We conducted a 2-year longitudinal, multisite study of 225 youth with type 1 diabetes recruited at the cusp of adolescence (aged 9-11 years) to describe the mutual influences of glycemic control as measured by HbA 1c and treatment adherence as measured by blood glucose monitoring frequency (BGMF) during the transition to adolescence. RESULTS - HbA 1c increased from 8.2 to 8.6% (P < 0.001) and BGMF decreased from 4.9 to 4.5 checks per day (P < 0.02) during the 2-year period. Changes in the BGMF slope predicted changes in HbA 1c. A change (increase) in HbA 1c was associated with a change (decrease) in BGMF of 1.26 (P < 0.001) after controlling for covariates. CONCLUSIONS - The magnitude of the effect of declining treatment adherence (BGMF) on glycemic control in young adolescents may be even greater than declines observed among older adolescents. BGMF offers a powerful tool for targeted management of glycemic control for type 1 diabetes during the critical transition to adolescence.
| Original language | English |
|---|---|
| Pages (from-to) | 1219-1224 |
| Number of pages | 6 |
| Journal | Diabetes Care |
| Volume | 35 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 1 2012 |
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ASJC Scopus subject areas
- Internal Medicine
- Endocrinology, Diabetes and Metabolism
- Advanced and Specialized Nursing
Cite this
Changes in treatment adherence and glycemic control during the transition to adolescence in type 1 diabetes. / Rausch, Joseph R.; Hood, Korey K.; Delamater, Alan M; Pendley, Jennifer Shroff; Rohan, Jennifer M.; Reeves, Grafton; Dolan, Lawrence; Drotar, Dennis.
In: Diabetes Care, Vol. 35, No. 6, 01.06.2012, p. 1219-1224.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Changes in treatment adherence and glycemic control during the transition to adolescence in type 1 diabetes
AU - Rausch, Joseph R.
AU - Hood, Korey K.
AU - Delamater, Alan M
AU - Pendley, Jennifer Shroff
AU - Rohan, Jennifer M.
AU - Reeves, Grafton
AU - Dolan, Lawrence
AU - Drotar, Dennis
PY - 2012/6/1
Y1 - 2012/6/1
N2 - OBJECTIVE - To test models of unidirectional and bidirectional change between treatment adherence and glycemic control in youth with type 1 diabetes. RESEARCH DESIGN AND METHODS - We conducted a 2-year longitudinal, multisite study of 225 youth with type 1 diabetes recruited at the cusp of adolescence (aged 9-11 years) to describe the mutual influences of glycemic control as measured by HbA 1c and treatment adherence as measured by blood glucose monitoring frequency (BGMF) during the transition to adolescence. RESULTS - HbA 1c increased from 8.2 to 8.6% (P < 0.001) and BGMF decreased from 4.9 to 4.5 checks per day (P < 0.02) during the 2-year period. Changes in the BGMF slope predicted changes in HbA 1c. A change (increase) in HbA 1c was associated with a change (decrease) in BGMF of 1.26 (P < 0.001) after controlling for covariates. CONCLUSIONS - The magnitude of the effect of declining treatment adherence (BGMF) on glycemic control in young adolescents may be even greater than declines observed among older adolescents. BGMF offers a powerful tool for targeted management of glycemic control for type 1 diabetes during the critical transition to adolescence.
AB - OBJECTIVE - To test models of unidirectional and bidirectional change between treatment adherence and glycemic control in youth with type 1 diabetes. RESEARCH DESIGN AND METHODS - We conducted a 2-year longitudinal, multisite study of 225 youth with type 1 diabetes recruited at the cusp of adolescence (aged 9-11 years) to describe the mutual influences of glycemic control as measured by HbA 1c and treatment adherence as measured by blood glucose monitoring frequency (BGMF) during the transition to adolescence. RESULTS - HbA 1c increased from 8.2 to 8.6% (P < 0.001) and BGMF decreased from 4.9 to 4.5 checks per day (P < 0.02) during the 2-year period. Changes in the BGMF slope predicted changes in HbA 1c. A change (increase) in HbA 1c was associated with a change (decrease) in BGMF of 1.26 (P < 0.001) after controlling for covariates. CONCLUSIONS - The magnitude of the effect of declining treatment adherence (BGMF) on glycemic control in young adolescents may be even greater than declines observed among older adolescents. BGMF offers a powerful tool for targeted management of glycemic control for type 1 diabetes during the critical transition to adolescence.
UR - http://www.scopus.com/inward/record.url?scp=84861762791&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84861762791&partnerID=8YFLogxK
U2 - 10.2337/dc11-2163
DO - 10.2337/dc11-2163
M3 - Article
C2 - 22474040
AN - SCOPUS:84861762791
VL - 35
SP - 1219
EP - 1224
JO - Diabetes Care
JF - Diabetes Care
SN - 1935-5548
IS - 6
ER -