Changes in treatment adherence and glycemic control during the transition to adolescence in type 1 diabetes

Joseph R. Rausch, Korey K. Hood, Alan M Delamater, Jennifer Shroff Pendley, Jennifer M. Rohan, Grafton Reeves, Lawrence Dolan, Dennis Drotar

Research output: Contribution to journalArticle

87 Citations (Scopus)

Abstract

OBJECTIVE - To test models of unidirectional and bidirectional change between treatment adherence and glycemic control in youth with type 1 diabetes. RESEARCH DESIGN AND METHODS - We conducted a 2-year longitudinal, multisite study of 225 youth with type 1 diabetes recruited at the cusp of adolescence (aged 9-11 years) to describe the mutual influences of glycemic control as measured by HbA 1c and treatment adherence as measured by blood glucose monitoring frequency (BGMF) during the transition to adolescence. RESULTS - HbA 1c increased from 8.2 to 8.6% (P < 0.001) and BGMF decreased from 4.9 to 4.5 checks per day (P < 0.02) during the 2-year period. Changes in the BGMF slope predicted changes in HbA 1c. A change (increase) in HbA 1c was associated with a change (decrease) in BGMF of 1.26 (P < 0.001) after controlling for covariates. CONCLUSIONS - The magnitude of the effect of declining treatment adherence (BGMF) on glycemic control in young adolescents may be even greater than declines observed among older adolescents. BGMF offers a powerful tool for targeted management of glycemic control for type 1 diabetes during the critical transition to adolescence.

Original languageEnglish
Pages (from-to)1219-1224
Number of pages6
JournalDiabetes Care
Volume35
Issue number6
DOIs
StatePublished - Jun 1 2012

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Type 1 Diabetes Mellitus
Blood Glucose
Therapeutics
Longitudinal Studies
Research Design

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Advanced and Specialized Nursing

Cite this

Rausch, J. R., Hood, K. K., Delamater, A. M., Pendley, J. S., Rohan, J. M., Reeves, G., ... Drotar, D. (2012). Changes in treatment adherence and glycemic control during the transition to adolescence in type 1 diabetes. Diabetes Care, 35(6), 1219-1224. https://doi.org/10.2337/dc11-2163

Changes in treatment adherence and glycemic control during the transition to adolescence in type 1 diabetes. / Rausch, Joseph R.; Hood, Korey K.; Delamater, Alan M; Pendley, Jennifer Shroff; Rohan, Jennifer M.; Reeves, Grafton; Dolan, Lawrence; Drotar, Dennis.

In: Diabetes Care, Vol. 35, No. 6, 01.06.2012, p. 1219-1224.

Research output: Contribution to journalArticle

Rausch, JR, Hood, KK, Delamater, AM, Pendley, JS, Rohan, JM, Reeves, G, Dolan, L & Drotar, D 2012, 'Changes in treatment adherence and glycemic control during the transition to adolescence in type 1 diabetes', Diabetes Care, vol. 35, no. 6, pp. 1219-1224. https://doi.org/10.2337/dc11-2163
Rausch, Joseph R. ; Hood, Korey K. ; Delamater, Alan M ; Pendley, Jennifer Shroff ; Rohan, Jennifer M. ; Reeves, Grafton ; Dolan, Lawrence ; Drotar, Dennis. / Changes in treatment adherence and glycemic control during the transition to adolescence in type 1 diabetes. In: Diabetes Care. 2012 ; Vol. 35, No. 6. pp. 1219-1224.
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