Changes in the interstitial fluid and the muscle water in rabbits in hemorrhagic shock

M. W. Wolcott, T. I. Malinin, N. M. Wu

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Dynamics and changes in the biochemical composition in the interstitial fluid and the muscle water were studied in hemorrhagic shock. The interstitial fluid was collected from implanted perforated capsules. Muscle biopsies were examined with regard to their water content by the steady state magnetic nuclear resonance spectroscopy. The consistent and what appears to be the most significant changes were the fall in the interstitial fluid pressures, the quantitative reduction of muscle water, a sharp fall in the blood and interstitial blood pH, the moderate hyperkalemia and lack of change in blood and interstitial fluid sodium, and the rise in blood glucose levels not accompanied by a rise in the interstitial fluid glucose levels.

Original languageEnglish (US)
Pages (from-to)728-733
Number of pages6
JournalAnnals of surgery
Volume184
Issue number6
DOIs
StatePublished - Jan 1 1976

ASJC Scopus subject areas

  • Surgery

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