Changes in the condyle and disc in response to distraction osteogenesis of the minipig mandible

Petra Thurmuumlller, Maria J. Troulis, Andrew Rosenberg, Leonard B. Kaban

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Purpose: Distraction osteogenesis (DO) is a commonly used technique for mandibular lengthening, but changes in the temporomandibular joint have not been well documented. The purpose of this study was to evaluate the effect of DO, at varying rates, on the mandibular condyle and articular disc. Materials and Methods: Semiburied distractors were placed via submandibular incisions in 15 minipigs. Two unoperated animals served as controls. The protocol consisted of 0 day latency and rates of 1, 2, or 4 mm/d for a 12-mm gap. After the animals were killed (0, 24, or 90 days), ipsilateral and contralateral condyles and discs were harvested and evaluated to determine changes in 1) condylar form and size, 2) condylar surface, and 3) the articular disc. Results: Articular surfaces of the condyles in control animals were smooth, with no irregularities or erosions. In animals undergoing distraction, ipsilateral condyles showed increasing changes in morphology and AP dimension, and surface contour irregularities as the DO rate increased. These changes were present, but to a lesser degree, in the contralateral condyles. Articular discs of both ipsilateral and contralateral sides showed variable thinning at the medial aspect at end DO. After 90 days, changes in the condyles and discs were reduced by remodeling except in the 4 mm/d DO groups. Conclusions: Results of this preliminary study indicate that gross changes occur in condyles and discs after unilateral mandibular DO. These changes are more severe at faster distraction rates (4 mm/d) and tend to resolve during neutral fixation when a rate of 1 mm/d is used.

Original languageEnglish
Pages (from-to)1327-1333
Number of pages7
JournalJournal of Oral and Maxillofacial Surgery
Volume60
Issue number11
DOIs
StatePublished - Nov 1 2002
Externally publishedYes

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Distraction Osteogenesis
Miniature Swine
Mandible
Bone and Bones
Joints
Mandibular Condyle
Temporomandibular Joint

ASJC Scopus subject areas

  • Dentistry(all)
  • Surgery

Cite this

Changes in the condyle and disc in response to distraction osteogenesis of the minipig mandible. / Thurmuumlller, Petra; Troulis, Maria J.; Rosenberg, Andrew; Kaban, Leonard B.

In: Journal of Oral and Maxillofacial Surgery, Vol. 60, No. 11, 01.11.2002, p. 1327-1333.

Research output: Contribution to journalArticle

Thurmuumlller, Petra ; Troulis, Maria J. ; Rosenberg, Andrew ; Kaban, Leonard B. / Changes in the condyle and disc in response to distraction osteogenesis of the minipig mandible. In: Journal of Oral and Maxillofacial Surgery. 2002 ; Vol. 60, No. 11. pp. 1327-1333.
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