Changes in Kaposi's sarcoma induced by dapsone

P. A. Fanti, Antonella Tosti, S. Pileri

Research output: Contribution to journalArticle

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Abstract

The authors describe the clinical and histological changes in well-established classic Kaposi's sarcoma lesions during 2-years therapy with dapsone. Both the patients noted a great improvement in their symptoms. Clinical examination did not show significant modifications of the lesions. Histology showed a striking reduction in the spindle-cell component and an increase in the number of mature vessels. Immunohistochemistry with an endothelial cell marker (FVIIIRAg) confirmed the presence of an increased number of mature vessels after treatment. This study seems to confirm that dapsone can modify well-established lesions of classic Kaposi's sarcoma.

Original languageEnglish
Pages (from-to)441-443
Number of pages3
JournalClinical and Experimental Dermatology
Volume16
Issue number6
StatePublished - Jan 1 1991
Externally publishedYes

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Dapsone
Kaposi's Sarcoma
Cellular Structures
Histology
Endothelial Cells
Immunohistochemistry
Therapeutics

ASJC Scopus subject areas

  • Dermatology

Cite this

Changes in Kaposi's sarcoma induced by dapsone. / Fanti, P. A.; Tosti, Antonella; Pileri, S.

In: Clinical and Experimental Dermatology, Vol. 16, No. 6, 01.01.1991, p. 441-443.

Research output: Contribution to journalArticle

Fanti, PA, Tosti, A & Pileri, S 1991, 'Changes in Kaposi's sarcoma induced by dapsone', Clinical and Experimental Dermatology, vol. 16, no. 6, pp. 441-443.
Fanti, P. A. ; Tosti, Antonella ; Pileri, S. / Changes in Kaposi's sarcoma induced by dapsone. In: Clinical and Experimental Dermatology. 1991 ; Vol. 16, No. 6. pp. 441-443.
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