Changes in blood constituents of guinea pigs in lantana toxicity

O. P. Sharma, H. P.S. Makkar, Rajinder Dawra, S. S. Negi

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Lantana toxicity of guinea pigs elicited an increase in hematocrit, erythrocyte and leukocyte number, hemoglobin, urea-nitrogen and bilirubin contents in the blood of the affected animals. Most of the bilirubin was present in the conjugated form. Enzyme activities of glutamic oxaloacetic transaminase, acid phosphatase, lactate dehydrogenase, glutamate dehydrogenase, sorbitol dehydrogenase in the blood plasma of affected animals exhibited a marked increase. Acid phosphatase activity was inhibited by tartrate. Enzyme activity of alkaline phosphatase remained unchanged while that of glutamic pyruvic transaminase showed a marginal decrease.

Original languageEnglish (US)
Pages (from-to)73-76
Number of pages4
JournalToxicology Letters
Volume11
Issue number1-2
DOIs
StatePublished - Jan 1 1982
Externally publishedYes

Fingerprint

Lantana
Enzyme activity
Acid Phosphatase
Bilirubin
Toxicity
Guinea Pigs
Animals
Blood
L-Iditol 2-Dehydrogenase
Oxaloacetic Acid
Glutamate Dehydrogenase
Erythrocyte Count
Enzymes
Aspartate Aminotransferases
Alanine Transaminase
Leukocyte Count
Hematocrit
L-Lactate Dehydrogenase
Phosphoric Monoester Hydrolases
Alkaline Phosphatase

ASJC Scopus subject areas

  • Toxicology

Cite this

Changes in blood constituents of guinea pigs in lantana toxicity. / Sharma, O. P.; Makkar, H. P.S.; Dawra, Rajinder; Negi, S. S.

In: Toxicology Letters, Vol. 11, No. 1-2, 01.01.1982, p. 73-76.

Research output: Contribution to journalArticle

Sharma, O. P. ; Makkar, H. P.S. ; Dawra, Rajinder ; Negi, S. S. / Changes in blood constituents of guinea pigs in lantana toxicity. In: Toxicology Letters. 1982 ; Vol. 11, No. 1-2. pp. 73-76.
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