Chained lightning, part II: Neurosurgical principles, radiosurgical technology, and the manipulation of energy beam delivery

Daniel J. Hoh, Charles Y. Liu, Joseph C T Chen, Paul G. Pagnini, Cheng Yu, Michael Y. Wang, Michael L J Apuzzo

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

THE FUNDAMENTAL PRINCIPLE in the radiosurgical treatment of neurological conditions is the delivery of energy to a lesion with minimal injury to surrounding structures. The development of radiosurgical techniques from Leksell's original design has focused on the refinement of various methodologies to achieve energy containment within a target. This article is the second in a series reviewing the evolution of radiosurgical instruments with respect to issues of energy beam generation and delivery for improved conformal therapy.Continuing with concepts introduced in an earlier article, this article examines specific aspects of beam delivery and the emergence of stereotactic radiosurgery as a measure for focusing energy beams within a target volume. The application of stereotactic principles and devices to gamma ray and linear accelerator-based energy sources provides the methodology by which energy beams are generated and targeted precisely in a focal lesion. Advanced technological systems are reviewed, including fixed beams, dynamic radiosurgery, multileaf collimation, beam shaping, and robotics as various approaches for manipulating beam delivery. Radiosurgical instruments are also compared with regard to mechanics, geometry, and dosimetry. Finally, new radiosurgical designs currently on the horizon are introduced. In exploring the complex history of radiosurgery, it is evident that the discovery and rediscovery of ideas invariably leads to the development of innovative technology for the next generation.

Original languageEnglish
Pages (from-to)433-446
Number of pages14
JournalNeurosurgery
Volume61
Issue number3
DOIs
StatePublished - Sep 1 2007
Externally publishedYes

Fingerprint

Lightning
Radiosurgery
Technology
Particle Accelerators
Gamma Rays
Robotics
Mechanics
History
Equipment and Supplies
Wounds and Injuries
Therapeutics

Keywords

  • Medical technology
  • Minimally invasive surgery
  • Radiation oncology
  • Radiation physics
  • Radiosurgery
  • Radiotherapy
  • Stereotactic neurosurgery

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Hoh, D. J., Liu, C. Y., Chen, J. C. T., Pagnini, P. G., Yu, C., Wang, M. Y., & Apuzzo, M. L. J. (2007). Chained lightning, part II: Neurosurgical principles, radiosurgical technology, and the manipulation of energy beam delivery. Neurosurgery, 61(3), 433-446. https://doi.org/10.1227/01.NEU.0000290888.54578.F5

Chained lightning, part II : Neurosurgical principles, radiosurgical technology, and the manipulation of energy beam delivery. / Hoh, Daniel J.; Liu, Charles Y.; Chen, Joseph C T; Pagnini, Paul G.; Yu, Cheng; Wang, Michael Y.; Apuzzo, Michael L J.

In: Neurosurgery, Vol. 61, No. 3, 01.09.2007, p. 433-446.

Research output: Contribution to journalArticle

Hoh, Daniel J. ; Liu, Charles Y. ; Chen, Joseph C T ; Pagnini, Paul G. ; Yu, Cheng ; Wang, Michael Y. ; Apuzzo, Michael L J. / Chained lightning, part II : Neurosurgical principles, radiosurgical technology, and the manipulation of energy beam delivery. In: Neurosurgery. 2007 ; Vol. 61, No. 3. pp. 433-446.
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