Cerebrovascular Complications in Early Survivors of Civilian Penetrating Brain Injury

Ali Mansour, Andrea Loggini, Faten El Ammar, Daniel Ginat, Issam A. Awad, Christos Lazaridis, Christopher Kramer, Valentina Vasenina, Sean P. Polster, Anna Huang, Henry Olivera Perez, Paramita Das, Peleg M. Horowitz, Tanya Zakrison, David Hampton, Selwyn O. Rogers, Fernando D. Goldenberg

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Background: This study investigates the presence of cerebrovascular injuries in a large sample of civilian penetrating brain injury (PBI) patients, determining the prevalence, radiographic characteristics, and impact on short-term outcome. Methods: We retrospectively reviewed patients with PBI admitted to our institution over a 2-year period. Computed tomography head scans, computer tomography angiograms and venograms of the intracranial vessels were evaluated to determine the wound trajectory, intracranial injury characteristics, and presence of arterial (AI) and venous sinus (VSI) injuries. Demographics, clinical presentation, and treatment were also reviewed. Discharge disposition was used as surrogate of short-term outcome. Results: Seventy-two patients were included in the study. The mechanism of injury was gunshot wounds in 71 patients and stab wound in one. Forty-one of the 72 patients (60%) had at least one vascular injury. Twenty-six out of 72 patients suffered an AI (36%), mostly pseudoaneurysms and occlusions, involving the anterior and middle cerebral arteries. Of the 72 patients included, 45 had dedicated computed tomography venograms, and of those 22 had VSI (49%), mainly manifesting as superior sagittal sinus occlusion. In a multivariable regression model, intraventricular hemorrhage at presentation was associated with AI (OR 9.9, p = 0.004). The same was not true for VSI. Conclusion: Acute traumatic cerebrovascular injury is a prevalent complication in civilian PBI, frequently involving both the arterial and venous sinus systems. Although some radiographic features might be associated with presence of vascular injury, assessment of the intracranial vasculature in the acute phase of all PBI is essential for early diagnosis. Treatment of vascular injury remains variable depending on local practice.

Original languageEnglish (US)
Pages (from-to)918-926
Number of pages9
JournalNeurocritical Care
Volume34
Issue number3
DOIs
StatePublished - Jun 2021
Externally publishedYes

Keywords

  • Cerebrovascular injury
  • Neurotrauma
  • Penetrating brain injury

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Clinical Neurology

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