Abstract
Cerebrospinal fluid T and B lymphocyte populations were identified in 21 patients with relapsing and 10 patients with stable multiple sclerosis. The results indicate that the percentage of T cells is largest in the acute stage of a relapse (65%) and diminishes by the second week (41%). Conversely, the stable patients have a lower percentage of T cells (30%) and a relatively high percentage of nonreacting cells (66%). The proportion of T cells in the cerebrospinal fluid varies directly with the clinical activity of the disorder, further implicating cellular immune mechanisms in the pathogenesis of multiple sclerosis.
Original language | English (US) |
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Pages (from-to) | 579-583 |
Number of pages | 5 |
Journal | Unknown Journal |
Volume | 26 |
Issue number | 6 I |
DOIs | |
State | Published - 1976 |
ASJC Scopus subject areas
- Clinical Neurology