Abstract
The authors examined the effects of antipsychotic treatment on cerebrospinal fluid somatostatin like immunoreactivity (CSF SLI) in 14 schizophrenic and 3 schizoaffective patients. There was a modest but significant increase in CSF SLI in 13 out of the 14 schizophrenic patients. In addition, there was a significant positive correlation between duration of treatment and post-treatment CSF SLI concentrations. No differential response was noted in patients also treated with the anticholinergic benztropine.
| Original language | English |
|---|---|
| Pages (from-to) | 173-177 |
| Number of pages | 5 |
| Journal | Schizophrenia Research |
| Volume | 13 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 1 1994 |
| Externally published | Yes |
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Keywords
- Antipsychotic
- Homovanillic acid
- Somatostatin
ASJC Scopus subject areas
- Psychology(all)
- Psychiatry and Mental health
- Behavioral Neuroscience
- Biological Psychiatry
- Neurology
Cite this
Cerebrospinal fluid somatostatin concentrations in schizophrenia and schizoaffective disorder : the effects of antipsychotic treatment. / Sharma, Rajiv P.; Bissette, Garth; Janicak, Philip; Davis, John M.; Nemeroff, Charles.
In: Schizophrenia Research, Vol. 13, No. 2, 01.01.1994, p. 173-177.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cerebrospinal fluid somatostatin concentrations in schizophrenia and schizoaffective disorder
T2 - the effects of antipsychotic treatment
AU - Sharma, Rajiv P.
AU - Bissette, Garth
AU - Janicak, Philip
AU - Davis, John M.
AU - Nemeroff, Charles
PY - 1994/1/1
Y1 - 1994/1/1
N2 - The authors examined the effects of antipsychotic treatment on cerebrospinal fluid somatostatin like immunoreactivity (CSF SLI) in 14 schizophrenic and 3 schizoaffective patients. There was a modest but significant increase in CSF SLI in 13 out of the 14 schizophrenic patients. In addition, there was a significant positive correlation between duration of treatment and post-treatment CSF SLI concentrations. No differential response was noted in patients also treated with the anticholinergic benztropine.
AB - The authors examined the effects of antipsychotic treatment on cerebrospinal fluid somatostatin like immunoreactivity (CSF SLI) in 14 schizophrenic and 3 schizoaffective patients. There was a modest but significant increase in CSF SLI in 13 out of the 14 schizophrenic patients. In addition, there was a significant positive correlation between duration of treatment and post-treatment CSF SLI concentrations. No differential response was noted in patients also treated with the anticholinergic benztropine.
KW - Antipsychotic
KW - Homovanillic acid
KW - Somatostatin
UR - http://www.scopus.com/inward/record.url?scp=0028021031&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028021031&partnerID=8YFLogxK
U2 - 10.1016/0920-9964(94)90099-X
DO - 10.1016/0920-9964(94)90099-X
M3 - Article
C2 - 7986775
AN - SCOPUS:0028021031
VL - 13
SP - 173
EP - 177
JO - Schizophrenia Research
JF - Schizophrenia Research
SN - 0920-9964
IS - 2
ER -