Cerebral haemodynamic changes during a migraine attack

A. Lovrencic-Huzjan, V. Demarin, T. Rundek, V. Seric

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Background and purpose: Data about changes of cerebral blood flow in migraine are still controversial. It is obscure whether migraine with aura and migraine without aura are different diseases or different types of the same disease. In order to assess changes of cerebral haemodynamics we analysed 21 migraine patients. Patients and methods: There were 8 migraine patients with aura and 13 without aura. Blood flow velocities (BFV) were measured by Transcranial Doppler (TCD) during headache-free period and migraine attack. We analysed mean BFV and pulsatility index (PI) in all branches of the Willis circle and vertebrobasilar system. Results: The majority of migraine patients had BFV within normal ranges. BFV were higher in patients with migraine without aura compared with patients with aura. During attack in patients with migraine with aura, decreased BFV and increased PI was observed, indicating vasoconstriction, leading to hypoperfusion. During attack in migraine without aura, increased systolic BFV and PI was found indicating lower vascular resistance. Conclusions: Our findings suggest different haemodynamic pattern between migraine with aura and migraine without aura.

Original languageEnglish (US)
Pages (from-to)127-131
Number of pages5
JournalPeriodicum Biologorum
Issue number2
StatePublished - 1995
Externally publishedYes


  • Doppler (TCD)
  • Migraine
  • Transcranial

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)


Dive into the research topics of 'Cerebral haemodynamic changes during a migraine attack'. Together they form a unique fingerprint.

Cite this