Abstract
The non-invasive xenon-133 inhalation technique was used to measure regional cerebral blood flow in 61 patients with cerebrovascular disease in whom carotid angiography had been performed before carotid endarterectomy or extracranial/intracranial arterial bypass were considered. Hemispheric cerebral blood flow (CBF) was significantly lower in patients with an ipsilateral internal carotid artery occlusion than in those with a patent vessel. CBF values were also influenced by disease of the contralateral carotid artery. The cerebrovascular response to hypercapnia was a more sensitive index of carotid disease; a significant reduction in CO2 responsiveness was found both with occlusion and stenosis of the ipsilateral internal carotid artery. These data suggest that CBF measurements may be clinically useful in selecting patients for angiography and surgery.
| Original language | English |
|---|---|
| Pages (from-to) | 429-431 |
| Number of pages | 3 |
| Journal | South African Medical Journal |
| Volume | 65 |
| Issue number | 11 |
| State | Published - Jan 1 1984 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
Cerebral blood flow measurement as an indicator of the haemodynamic severity of carotid artery disease in man. / Bullock, Ross; Mendelow, A. D.; Patterson, J.; Bone, I.
In: South African Medical Journal, Vol. 65, No. 11, 01.01.1984, p. 429-431.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cerebral blood flow measurement as an indicator of the haemodynamic severity of carotid artery disease in man
AU - Bullock, Ross
AU - Mendelow, A. D.
AU - Patterson, J.
AU - Bone, I.
PY - 1984/1/1
Y1 - 1984/1/1
N2 - The non-invasive xenon-133 inhalation technique was used to measure regional cerebral blood flow in 61 patients with cerebrovascular disease in whom carotid angiography had been performed before carotid endarterectomy or extracranial/intracranial arterial bypass were considered. Hemispheric cerebral blood flow (CBF) was significantly lower in patients with an ipsilateral internal carotid artery occlusion than in those with a patent vessel. CBF values were also influenced by disease of the contralateral carotid artery. The cerebrovascular response to hypercapnia was a more sensitive index of carotid disease; a significant reduction in CO2 responsiveness was found both with occlusion and stenosis of the ipsilateral internal carotid artery. These data suggest that CBF measurements may be clinically useful in selecting patients for angiography and surgery.
AB - The non-invasive xenon-133 inhalation technique was used to measure regional cerebral blood flow in 61 patients with cerebrovascular disease in whom carotid angiography had been performed before carotid endarterectomy or extracranial/intracranial arterial bypass were considered. Hemispheric cerebral blood flow (CBF) was significantly lower in patients with an ipsilateral internal carotid artery occlusion than in those with a patent vessel. CBF values were also influenced by disease of the contralateral carotid artery. The cerebrovascular response to hypercapnia was a more sensitive index of carotid disease; a significant reduction in CO2 responsiveness was found both with occlusion and stenosis of the ipsilateral internal carotid artery. These data suggest that CBF measurements may be clinically useful in selecting patients for angiography and surgery.
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UR - http://www.scopus.com/inward/citedby.url?scp=0021344087&partnerID=8YFLogxK
M3 - Article
C2 - 6701703
AN - SCOPUS:0021344087
VL - 65
SP - 429
EP - 431
JO - South African Medical Journal
JF - South African Medical Journal
SN - 0038-2469
IS - 11
ER -