Cell-mediated mineralization model for bioprosthetic heart valve tissue

Grace Ng, Ned H C Hwang, Herman S Cheung

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Calcification is the major cause of degeneration in bioprosthetic heart valves. One possible solution to the problem is to coat the surface of the heart valve with anti-mineralization agents, which are known to inhibit soft tissue calcification e.g. phosphocitrate and bisphoshonates. However, there are a few steps that must be performed before coating the surface of the heart valve with these agents. The focus of this paper is on these intermediate steps, which led to the design of a cell-mediated mineralization model for bioprosthetic heart valve tissue.

Original languageEnglish
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Place of PublicationPiscataway, NJ, United States
PublisherIEEE
Volume2
ISBN (Print)0780356756
StatePublished - Dec 1 1999
EventProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) - Atlanta, GA, USA
Duration: Oct 13 1999Oct 16 1999

Other

OtherProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
CityAtlanta, GA, USA
Period10/13/9910/16/99

Fingerprint

Tissue
Coatings
phosphocitrate

ASJC Scopus subject areas

  • Bioengineering

Cite this

Ng, G., Hwang, N. H. C., & Cheung, H. S. (1999). Cell-mediated mineralization model for bioprosthetic heart valve tissue. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 2). Piscataway, NJ, United States: IEEE.

Cell-mediated mineralization model for bioprosthetic heart valve tissue. / Ng, Grace; Hwang, Ned H C; Cheung, Herman S.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 2 Piscataway, NJ, United States : IEEE, 1999.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Ng, G, Hwang, NHC & Cheung, HS 1999, Cell-mediated mineralization model for bioprosthetic heart valve tissue. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. vol. 2, IEEE, Piscataway, NJ, United States, Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS), Atlanta, GA, USA, 10/13/99.
Ng G, Hwang NHC, Cheung HS. Cell-mediated mineralization model for bioprosthetic heart valve tissue. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 2. Piscataway, NJ, United States: IEEE. 1999
Ng, Grace ; Hwang, Ned H C ; Cheung, Herman S. / Cell-mediated mineralization model for bioprosthetic heart valve tissue. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 2 Piscataway, NJ, United States : IEEE, 1999.
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