Abstract
Taste bud cells communicate with sensory afferent fibers and may also exchange information with adjacent cells. Indeed, communication between taste cells via conventional and/or novel synaptic interactions may occur prior to signal output to primary afferent fibers. This review discusses synaptic processing in taste buds and summarizes results showing that it is now possible to measure real-time release of synaptic transmitters during taste stimulation using cellular biosensors. There is strong evidence that serotonin and ATP play a role in cell-to-cell signaling and sensory output in the gustatory end organs.
| Original language | English |
|---|---|
| Pages (from-to) | 1494-1500 |
| Number of pages | 7 |
| Journal | Cellular and Molecular Life Sciences |
| Volume | 63 |
| Issue number | 13 |
| DOIs | |
| State | Published - Jul 1 2006 |
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Keywords
- ATP
- Paracrine
- Sensory afferent fibers
- Serotonin
- Synapses
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Cell Biology
Cite this
Cell communication in taste buds. / Roper, Stephen D.
In: Cellular and Molecular Life Sciences, Vol. 63, No. 13, 01.07.2006, p. 1494-1500.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cell communication in taste buds
AU - Roper, Stephen D
PY - 2006/7/1
Y1 - 2006/7/1
N2 - Taste bud cells communicate with sensory afferent fibers and may also exchange information with adjacent cells. Indeed, communication between taste cells via conventional and/or novel synaptic interactions may occur prior to signal output to primary afferent fibers. This review discusses synaptic processing in taste buds and summarizes results showing that it is now possible to measure real-time release of synaptic transmitters during taste stimulation using cellular biosensors. There is strong evidence that serotonin and ATP play a role in cell-to-cell signaling and sensory output in the gustatory end organs.
AB - Taste bud cells communicate with sensory afferent fibers and may also exchange information with adjacent cells. Indeed, communication between taste cells via conventional and/or novel synaptic interactions may occur prior to signal output to primary afferent fibers. This review discusses synaptic processing in taste buds and summarizes results showing that it is now possible to measure real-time release of synaptic transmitters during taste stimulation using cellular biosensors. There is strong evidence that serotonin and ATP play a role in cell-to-cell signaling and sensory output in the gustatory end organs.
KW - ATP
KW - Paracrine
KW - Sensory afferent fibers
KW - Serotonin
KW - Synapses
UR - http://www.scopus.com/inward/record.url?scp=33746607323&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33746607323&partnerID=8YFLogxK
U2 - 10.1007/s00018-006-6112-9
DO - 10.1007/s00018-006-6112-9
M3 - Article
C2 - 16732426
AN - SCOPUS:33746607323
VL - 63
SP - 1494
EP - 1500
JO - Cellular and Molecular Life Sciences
JF - Cellular and Molecular Life Sciences
SN - 1420-682X
IS - 13
ER -