Celiac disease and alopecia areata

Report of a new association

Gino R. Corazza, Maria L. Andreani, Nicola Venturo, Mauro Bernardi, Antonella Tosti, Giovanni Gasbarrini

Research output: Contribution to journalArticle

103 Citations (Scopus)

Abstract

Celiac disease is frequently associated with other auto-immune disorders but has never been reported in association with alopecia areata. In a routine clinical practice, 3 patients with such an association were observed. In one of the patients, celiac disease was diagnosed after the occurrence of malabsorption symptoms. In the youngest patient, a 14-year-old boy, glutenfree diet resulted in complete regrowth of scalp and body hair. A prospective screening program for celiac disease using antigliadin and antiendomysial antibodies was therefore set up in 256 consecutive outpatients with alopecia areata. Three patients, all completely asymptomatic for intestinal diseases, were found to be positive and underwent biopsy. Histological analysis showed a flat intestinal mucosa consistent with the diagnosis of celiac disease. The results show that alopecia areata may constitute the only clinical manifestation of celiac disease and that the association between these two conditions is a real one because the observed frequency of association is much greater than can be expected by chance. It is suggested that antigliadin and antiendomysial antibodies should be included in the work-up of patients with alopecia areata.

Original languageEnglish
Pages (from-to)1333-1337
Number of pages5
JournalGastroenterology
Volume109
Issue number4
DOIs
StatePublished - Jan 1 1995
Externally publishedYes

Fingerprint

Alopecia Areata
Celiac Disease
Asymptomatic Diseases
Intestinal Diseases
Antibodies
Immune System Diseases
Intestinal Mucosa
Scalp
Hair
Outpatients
Diet
Biopsy

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Corazza, G. R., Andreani, M. L., Venturo, N., Bernardi, M., Tosti, A., & Gasbarrini, G. (1995). Celiac disease and alopecia areata: Report of a new association. Gastroenterology, 109(4), 1333-1337. https://doi.org/10.1016/0016-5085(95)90597-9

Celiac disease and alopecia areata : Report of a new association. / Corazza, Gino R.; Andreani, Maria L.; Venturo, Nicola; Bernardi, Mauro; Tosti, Antonella; Gasbarrini, Giovanni.

In: Gastroenterology, Vol. 109, No. 4, 01.01.1995, p. 1333-1337.

Research output: Contribution to journalArticle

Corazza, GR, Andreani, ML, Venturo, N, Bernardi, M, Tosti, A & Gasbarrini, G 1995, 'Celiac disease and alopecia areata: Report of a new association', Gastroenterology, vol. 109, no. 4, pp. 1333-1337. https://doi.org/10.1016/0016-5085(95)90597-9
Corazza GR, Andreani ML, Venturo N, Bernardi M, Tosti A, Gasbarrini G. Celiac disease and alopecia areata: Report of a new association. Gastroenterology. 1995 Jan 1;109(4):1333-1337. https://doi.org/10.1016/0016-5085(95)90597-9
Corazza, Gino R. ; Andreani, Maria L. ; Venturo, Nicola ; Bernardi, Mauro ; Tosti, Antonella ; Gasbarrini, Giovanni. / Celiac disease and alopecia areata : Report of a new association. In: Gastroenterology. 1995 ; Vol. 109, No. 4. pp. 1333-1337.
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