Abstract
Tsukamurella is a Gram-positive, variable rod-shaped, weakly acid-alcohol-fast, non motile, aerobic bacterium that belongs to the genus Rhodococcus. Tsukamurella has been reported as a cause of infections in humans with immunosuppression and indwelling foreign bodies. It has also been isolated in one patient with AIDS (Acquired Immunodeficiency Syndrome) as a saprophytic organism. Optimal management of infections secondary to this micro-organism is still uncertain due to the paucity of cases. The combination of a beta-lactam and an aminoglycoside, along with removal of medical devices, appear to be the treatment of choice. We report the case of an AIDS patient who presented with multiple lung cavitary lesions secondary to Tsukamurella. This is the first case reported of Tsukamurella as a pathogenic agent in an AIDS patient. We also propose a successful oral antibiotic regimen with fluoroquinolone and rifampin to treat infections secondary to this uncommon micro-organism.
| Original language | English |
|---|---|
| Pages (from-to) | 17-19 |
| Number of pages | 3 |
| Journal | Journal of Infection |
| Volume | 49 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jul 1 2004 |
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Keywords
- AIDS
- Cavitations
- Pneumonia
- Tsukamurella
ASJC Scopus subject areas
- Applied Microbiology and Biotechnology
- Microbiology
- Parasitology
- Virology
- Immunology and Allergy
- Infectious Diseases
Cite this
Cavitary pneumonia secondary to Tsukamurella in an AIDS patient. First case and a review of the literature. / Alcaide, Maria L; Espinoza, Luis; Abbo, Lilian.
In: Journal of Infection, Vol. 49, No. 1, 01.07.2004, p. 17-19.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cavitary pneumonia secondary to Tsukamurella in an AIDS patient. First case and a review of the literature
AU - Alcaide, Maria L
AU - Espinoza, Luis
AU - Abbo, Lilian
PY - 2004/7/1
Y1 - 2004/7/1
N2 - Tsukamurella is a Gram-positive, variable rod-shaped, weakly acid-alcohol-fast, non motile, aerobic bacterium that belongs to the genus Rhodococcus. Tsukamurella has been reported as a cause of infections in humans with immunosuppression and indwelling foreign bodies. It has also been isolated in one patient with AIDS (Acquired Immunodeficiency Syndrome) as a saprophytic organism. Optimal management of infections secondary to this micro-organism is still uncertain due to the paucity of cases. The combination of a beta-lactam and an aminoglycoside, along with removal of medical devices, appear to be the treatment of choice. We report the case of an AIDS patient who presented with multiple lung cavitary lesions secondary to Tsukamurella. This is the first case reported of Tsukamurella as a pathogenic agent in an AIDS patient. We also propose a successful oral antibiotic regimen with fluoroquinolone and rifampin to treat infections secondary to this uncommon micro-organism.
AB - Tsukamurella is a Gram-positive, variable rod-shaped, weakly acid-alcohol-fast, non motile, aerobic bacterium that belongs to the genus Rhodococcus. Tsukamurella has been reported as a cause of infections in humans with immunosuppression and indwelling foreign bodies. It has also been isolated in one patient with AIDS (Acquired Immunodeficiency Syndrome) as a saprophytic organism. Optimal management of infections secondary to this micro-organism is still uncertain due to the paucity of cases. The combination of a beta-lactam and an aminoglycoside, along with removal of medical devices, appear to be the treatment of choice. We report the case of an AIDS patient who presented with multiple lung cavitary lesions secondary to Tsukamurella. This is the first case reported of Tsukamurella as a pathogenic agent in an AIDS patient. We also propose a successful oral antibiotic regimen with fluoroquinolone and rifampin to treat infections secondary to this uncommon micro-organism.
KW - AIDS
KW - Cavitations
KW - Pneumonia
KW - Tsukamurella
UR - http://www.scopus.com/inward/record.url?scp=3242663570&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=3242663570&partnerID=8YFLogxK
U2 - 10.1016/S0163-4453(03)00139-7
DO - 10.1016/S0163-4453(03)00139-7
M3 - Article
C2 - 15194243
AN - SCOPUS:3242663570
VL - 49
SP - 17
EP - 19
JO - Journal of Infection
JF - Journal of Infection
SN - 0163-4453
IS - 1
ER -