Cavitary pneumonia secondary to Tsukamurella in an AIDS patient. First case and a review of the literature

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Tsukamurella is a Gram-positive, variable rod-shaped, weakly acid-alcohol-fast, non motile, aerobic bacterium that belongs to the genus Rhodococcus. Tsukamurella has been reported as a cause of infections in humans with immunosuppression and indwelling foreign bodies. It has also been isolated in one patient with AIDS (Acquired Immunodeficiency Syndrome) as a saprophytic organism. Optimal management of infections secondary to this micro-organism is still uncertain due to the paucity of cases. The combination of a beta-lactam and an aminoglycoside, along with removal of medical devices, appear to be the treatment of choice. We report the case of an AIDS patient who presented with multiple lung cavitary lesions secondary to Tsukamurella. This is the first case reported of Tsukamurella as a pathogenic agent in an AIDS patient. We also propose a successful oral antibiotic regimen with fluoroquinolone and rifampin to treat infections secondary to this uncommon micro-organism.

Original languageEnglish
Pages (from-to)17-19
Number of pages3
JournalJournal of Infection
Volume49
Issue number1
DOIs
StatePublished - Jul 1 2004

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Pneumonia
Acquired Immunodeficiency Syndrome
Coinfection
Gram-Positive Rods
Rhodococcus
Aerobic Bacteria
Fluoroquinolones
beta-Lactams
Aminoglycosides
Rifampin
Foreign Bodies
Immunosuppression
Alcohols
Anti-Bacterial Agents
Equipment and Supplies
Lung
Acids
Infection
Therapeutics

Keywords

  • AIDS
  • Cavitations
  • Pneumonia
  • Tsukamurella

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Microbiology
  • Parasitology
  • Virology
  • Immunology and Allergy
  • Infectious Diseases

Cite this

Cavitary pneumonia secondary to Tsukamurella in an AIDS patient. First case and a review of the literature. / Alcaide, Maria L; Espinoza, Luis; Abbo, Lilian.

In: Journal of Infection, Vol. 49, No. 1, 01.07.2004, p. 17-19.

Research output: Contribution to journalArticle

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