Abstract
The aim of this study was to investigate the causes and seasonality of death and co-morbid conditions among progressive supranuclear palsy (PSP) patients. 22 consecutive clinicopathologically confirmed PSP patients were compared with 22 gender and age-matched Parkinson's disease (PD) patients and 26 non-neurological controls. All subjects consented during life to donate their brains to the University of Miami Brain Endowment Bank™. Respiratory-related deaths were significantly more frequent in PSP when compared to PD patients. Recurrent respiratory infections were also very frequent in PSP patients and were commonly associated with respiratory-related deaths. Deaths that occurred during winter and spring months accounted for about 70% of deaths among PSP patients. The most common co-morbid condition in PSP was hypertension, present in 50% of cases.
Original language | English (US) |
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Pages (from-to) | 459-463 |
Number of pages | 5 |
Journal | Parkinsonism and Related Disorders |
Volume | 11 |
Issue number | 7 |
DOIs | |
State | Published - Nov 1 2005 |
Keywords
- Brain donors
- Cause of death
- Post-mortem
- Progressive supranuclear palsy
- Seasonality
ASJC Scopus subject areas
- Aging
- Clinical Neurology
- Neurology