TY - JOUR
T1 - Caudate Hyperintensities in Elderly Depressed Patients With Neuroleptic-Induced Parkinsonism
AU - Figiel, Gary S.
AU - Krishnan, K. Ranga R.
AU - Doraiswamy, P. Murali
AU - Nemeroff, Charles B.
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1991/4
Y1 - 1991/4
N2 - Elderly patients are particularly sensitive to the neurologic side effects of psychotropic medications. This increased sensitivity may be related to brain structural changes associated with aging. In this pilot study, the authors report on the occurrence of caudate hyperintensities, using brain magnetic resonance imaging, in seven elderly depressed subjects who developed neuroleptic-induced parkinsonism. Caudate hyperintensities were not observed in any of the seven healthy elderly controls examined. These results suggest that caudate hyperintensities may render some elderly depressed patients susceptible to neuroleptic-induced parkinsonism.
AB - Elderly patients are particularly sensitive to the neurologic side effects of psychotropic medications. This increased sensitivity may be related to brain structural changes associated with aging. In this pilot study, the authors report on the occurrence of caudate hyperintensities, using brain magnetic resonance imaging, in seven elderly depressed subjects who developed neuroleptic-induced parkinsonism. Caudate hyperintensities were not observed in any of the seven healthy elderly controls examined. These results suggest that caudate hyperintensities may render some elderly depressed patients susceptible to neuroleptic-induced parkinsonism.
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U2 - 10.1177/089198879100400206
DO - 10.1177/089198879100400206
M3 - Article
C2 - 1677248
AN - SCOPUS:0025784733
VL - 4
SP - 86
EP - 89
JO - Journal of Geriatric Psychiatry and Neurology
JF - Journal of Geriatric Psychiatry and Neurology
SN - 0891-9887
IS - 2
ER -
