Catheter survival and comparison of catheter exchange methods in children on hemodialysis

Ali Mirza Onder, Jayanthi Chandar, Marie Saint-Vil, Gabriela Lopez-Mitnik, Carolyn Abitbol, Gaston E Zilleruelo

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

This retrospective study was done to compare the infection-free and overall survival of first and subsequent tunneled cuffed hemodialysis catheters in children. Subsequent catheters were exchanged by two different methods (a) removal and replacement (R&R), or (b) wire-guided exchange (WGE) using the same tunnel and vessel. The study involved 59 children (27 male, 32 female; mean age 13.9±4.6 years) undergoing maintenance hemodialysis in a pediatric unit over a period of 60 months. From a total of 175 catheters (57 first catheters, 81 WGE, 37 R&R) and 38,888 catheter days, 74/175 (42%) catheters were exchanged because of catheter-related bacteremia (CRB) and 43/175 (25%) for malfunction or cuff extrusion. One-year survival rates for first and consecutive catheters was 26% and 21%, respectively. The overall survival of first catheters, and those exchanged by WGE and R&R for both infectious and non-infectious reasons, was not statistically different. However, infection-free survival of first catheters was significantly prolonged in comparison with that of subsequent catheters (P<0.001). The infection-free survival and the overall survival were not affected by etiology of primary disease, gender, serum albumin, or hemoglobin. Overall catheter survival increased with age >10 years. There was a significant association between gram-negative and polymicrobial CRB and requirement for R&R (P<0.02). Our findings suggest that WGE is safe in a clinically stable child if the tunnel and the exit site are not infected and has the potential benefit of preserving the vascular access site. The shorter infection-free survival in subsequent catheters suggests a cumulative disadvantage with prolonged catheter use.

Original languageEnglish
Pages (from-to)1355-1361
Number of pages7
JournalPediatric Nephrology
Volume22
Issue number9
DOIs
StatePublished - Sep 1 2007

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Renal Dialysis
Catheters
Bacteremia
Infection
Blood Vessels
Retrospective Studies
Maintenance
Pediatrics

Keywords

  • Catheter exchange
  • Catheter survival in children
  • Tunneled cuffed hemodialysis catheters
  • Wire-guided exchange

ASJC Scopus subject areas

  • Nephrology
  • Pediatrics, Perinatology, and Child Health

Cite this

Catheter survival and comparison of catheter exchange methods in children on hemodialysis. / Onder, Ali Mirza; Chandar, Jayanthi; Saint-Vil, Marie; Lopez-Mitnik, Gabriela; Abitbol, Carolyn; Zilleruelo, Gaston E.

In: Pediatric Nephrology, Vol. 22, No. 9, 01.09.2007, p. 1355-1361.

Research output: Contribution to journalArticle

Onder, Ali Mirza ; Chandar, Jayanthi ; Saint-Vil, Marie ; Lopez-Mitnik, Gabriela ; Abitbol, Carolyn ; Zilleruelo, Gaston E. / Catheter survival and comparison of catheter exchange methods in children on hemodialysis. In: Pediatric Nephrology. 2007 ; Vol. 22, No. 9. pp. 1355-1361.
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