Catheter ablation of atrial arrhythmias in cardiac sarcoidosis

Jonathan M. Willner, Juan Viles Gonzalez, James O. Coffey, Adam S. Morgenthau, Davendra Mehta

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Ablation of Atrial Arrhythmias in Cardiac Sarcoidosis. Background:We previously reported on the incidence and clinical implications of supraventricular arrhythmia in patients with cardiac sarcoidosis (CS). The role of catheter ablation for the management of atrial arrhythmia (AA) in this patient population is unknown.

Methods and Results: One hundred consecutive patients with CS were monitored for the incidence of supraventricular arrhythmias. Those with persistent symptoms despite optimal medical therapy proceeded to catheter ablation. Following ablation, all patients were followed serially with Holter monitoring or device interrogation. Thirty-two (32%) patients had symptomatic supraventricular arrhythmias. Nine (28%) patients had symptomatic AA requiring catheter ablation for clinical indications. Mean age was 55 ± 11.6 years. Five (56%) patients had atrial fibrillation (AF), of whom 2 also had cavotricuspid isthmus ablation. Four patients had isolated atrial flutter: 2 patients with left atrial flutter, and 2 patients with cavotricuspid flutter. All other arrhythmias were ablated in the left atrium. Mean duration of follow-up was 1.8 ± 1.9 years. One patient with atypical atrial flutter, and one patient with AF have had recurrence; the remaining patients remain in sinus rhythm.

Conclusions: Our study suggests that AA in CS is frequently left atrial in origin. Catheter ablation appears to be effective and safe for the maintenance of sinus rhythm in patients with CS.

Original languageEnglish
Pages (from-to)958-963
Number of pages6
JournalJournal of Cardiovascular Electrophysiology
Volume25
Issue number9
DOIs
StatePublished - Jan 1 2014

Fingerprint

Catheter Ablation
Sarcoidosis
Cardiac Arrhythmias
Atrial Flutter
Atrial Fibrillation
Ambulatory Electrocardiography
Incidence
Heart Atria

Keywords

  • Atrial fibrillation
  • Atrial flutter
  • Cardiac sarcoid
  • Catheter ablation
  • Sarcoidosis
  • Tachyarrhythmias

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Cite this

Willner, J. M., Viles Gonzalez, J., Coffey, J. O., Morgenthau, A. S., & Mehta, D. (2014). Catheter ablation of atrial arrhythmias in cardiac sarcoidosis. Journal of Cardiovascular Electrophysiology, 25(9), 958-963. https://doi.org/10.1111/jce.12424

Catheter ablation of atrial arrhythmias in cardiac sarcoidosis. / Willner, Jonathan M.; Viles Gonzalez, Juan; Coffey, James O.; Morgenthau, Adam S.; Mehta, Davendra.

In: Journal of Cardiovascular Electrophysiology, Vol. 25, No. 9, 01.01.2014, p. 958-963.

Research output: Contribution to journalArticle

Willner, JM, Viles Gonzalez, J, Coffey, JO, Morgenthau, AS & Mehta, D 2014, 'Catheter ablation of atrial arrhythmias in cardiac sarcoidosis', Journal of Cardiovascular Electrophysiology, vol. 25, no. 9, pp. 958-963. https://doi.org/10.1111/jce.12424
Willner JM, Viles Gonzalez J, Coffey JO, Morgenthau AS, Mehta D. Catheter ablation of atrial arrhythmias in cardiac sarcoidosis. Journal of Cardiovascular Electrophysiology. 2014 Jan 1;25(9):958-963. https://doi.org/10.1111/jce.12424
Willner, Jonathan M. ; Viles Gonzalez, Juan ; Coffey, James O. ; Morgenthau, Adam S. ; Mehta, Davendra. / Catheter ablation of atrial arrhythmias in cardiac sarcoidosis. In: Journal of Cardiovascular Electrophysiology. 2014 ; Vol. 25, No. 9. pp. 958-963.
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