Case 22-1992: Pathogenesis of Cat Scratch Disease

Bradley A. Perkins, Bala Swaminathan, Lisa A. Jackson, Don J. Brenner, Jay D. Wenger, Russell L. Regnery, Douglas J. Wear, David M. Andrews, James T. Kurnick, Kathryn L. Ruoff

Research output: Contribution to journalLetter

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To the Editor: Case Record 22–1992 (May 28 issue)1 described a 6 1/2-year-old girl with a diagnosis of cat scratch disease. The addendum noted that Afipia felis was detected in the patient's lymph-node specimen by polymerase-chain-reaction (PCR) assay and suggested that this provided “support to the diagnosis of cat-scratch-bacillus—induced encephalopathy.” A. felis, formerly known as the “cat scratch bacillus,” was isolated from lymph nodes of patients with cat scratch disease and recently characterized.2 We have attempted to verify that A. felis was the etiologic agent of cat scratch disease by evaluating clinical specimens obtained from patients with the disorder…

Original languageEnglish (US)
Pages (from-to)1599-1601
Number of pages3
JournalNew England Journal of Medicine
Issue number22
StatePublished - Nov 26 1992

ASJC Scopus subject areas

  • Medicine(all)

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    Perkins, B. A., Swaminathan, B., Jackson, L. A., Brenner, D. J., Wenger, J. D., Regnery, R. L., Wear, D. J., Andrews, D. M., Kurnick, J. T., & Ruoff, K. L. (1992). Case 22-1992: Pathogenesis of Cat Scratch Disease. New England Journal of Medicine, 327(22), 1599-1601.