Carotid intima-media thickness (IMT): A surrogate marker of atherosclerosis

Tanja Rundek, Vida Demarin

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations


Atherosclerosis is chronic, progressive disease of the arterial wall with onset decades prior to its clinical manifestations. Carotid intima-media thickness (IMT) measurement by ultrasound is an important tool for evaluation of early stages of atherosclerosis. Also, carotid intima-media thickness can be used for assessment of therapeutic effect of various regimens. Carotid IMT is sensitive marker of atherosclerosis. The causal relationship between carotid IMT and the clinical endpoint has been established on the basis of epidemiological studies and clinical trials. The strength of carotid IMT as a marker of atherosclerosis is enhanced by the fact that it may yield pathophysiological information at an early stage of atherogenic process.

Original languageEnglish (US)
Pages (from-to)45-51
Number of pages7
JournalActa Clinica Croatica
Issue number1
StatePublished - Mar 1 2006
Externally publishedYes


  • Arteriosclerosis - diagnosis
  • Carotid arteries - pathology
  • Cerebrovascular disorders - etiology
  • Cerebrovascular disorders - pathology

ASJC Scopus subject areas

  • Medicine(all)


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