Carotid intima-media thickness (cIMT) and plaque from risk assessment and clinical use to genetic discoveries

Susanne Bartels, Angelica Ruiz Franco, Tatjana Rundek

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Carotid intima-media thickness (cIMT) and carotid plaque are ultrasound imaging measures of carotid atherosclerosis and strong predictors of future stroke, myocardial infarction and vascular death. The use of ultrasound measures of cIMT and carotid plaque as a screening tool in clinical practice however have been extremely limited by a lack of recognition of its value by medical communities, health care policy makers and a lack of reimbursement by thirdparty payers engaged in the delivery of vascular imaging services. This review addresses the role of cIMT and plaque in vascular disease risk prediction. Recent data from large population based studies on reclassification of the vascular risk using carotid ultrasound imaging markers is presented. In addition, the common clinical scenarios for the appropriate use of cIMT in clinical setting are summarized according to the recent study conducted by the Society of the Atherosclerosis Imaging and Prevention in collaboration with the International Atherosclerosis Society. This presentation is intended to provide a practical guide for use of cIMT and plaque to clinicians to promote optimal clinical use of cIMT and to researchers to direct cIMT and plaque research towards investigating environmental and genetic factors of a complex disorder - subclinical atherosclerosis - leading to future genetic discoveries and new anti-Atherosclerotic therapies.

Original languageEnglish
Pages (from-to)139-145
Number of pages7
JournalPerspectives in Medicine
Volume1-12
DOIs
StatePublished - Sep 1 2012

Fingerprint

Carotid Intima-Media Thickness
Blood Vessels
Ultrasonography
Atherosclerosis
Community Health Services
Carotid Artery Diseases
Health Policy
Administrative Personnel
Vascular Diseases
Stroke
Myocardial Infarction
Research Personnel
Research
Population

Keywords

  • Carotid artery
  • Carotid IMT
  • Plaque
  • Risk factors
  • Surrogate markers
  • Ultrasound

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Carotid intima-media thickness (cIMT) and plaque from risk assessment and clinical use to genetic discoveries. / Bartels, Susanne; Franco, Angelica Ruiz; Rundek, Tatjana.

In: Perspectives in Medicine, Vol. 1-12, 01.09.2012, p. 139-145.

Research output: Contribution to journalArticle

@article{ec0fc0dc167e4d36aa34d911698d6057,
title = "Carotid intima-media thickness (cIMT) and plaque from risk assessment and clinical use to genetic discoveries",
abstract = "Carotid intima-media thickness (cIMT) and carotid plaque are ultrasound imaging measures of carotid atherosclerosis and strong predictors of future stroke, myocardial infarction and vascular death. The use of ultrasound measures of cIMT and carotid plaque as a screening tool in clinical practice however have been extremely limited by a lack of recognition of its value by medical communities, health care policy makers and a lack of reimbursement by thirdparty payers engaged in the delivery of vascular imaging services. This review addresses the role of cIMT and plaque in vascular disease risk prediction. Recent data from large population based studies on reclassification of the vascular risk using carotid ultrasound imaging markers is presented. In addition, the common clinical scenarios for the appropriate use of cIMT in clinical setting are summarized according to the recent study conducted by the Society of the Atherosclerosis Imaging and Prevention in collaboration with the International Atherosclerosis Society. This presentation is intended to provide a practical guide for use of cIMT and plaque to clinicians to promote optimal clinical use of cIMT and to researchers to direct cIMT and plaque research towards investigating environmental and genetic factors of a complex disorder - subclinical atherosclerosis - leading to future genetic discoveries and new anti-Atherosclerotic therapies.",
keywords = "Carotid artery, Carotid IMT, Plaque, Risk factors, Surrogate markers, Ultrasound",
author = "Susanne Bartels and Franco, {Angelica Ruiz} and Tatjana Rundek",
year = "2012",
month = "9",
day = "1",
doi = "10.1016/j.permed.2012.01.006",
language = "English",
volume = "1-12",
pages = "139--145",
journal = "Perspectives in Medicine",
issn = "2211-968X",
publisher = "Elsevier GmbH",

}

TY - JOUR

T1 - Carotid intima-media thickness (cIMT) and plaque from risk assessment and clinical use to genetic discoveries

AU - Bartels, Susanne

AU - Franco, Angelica Ruiz

AU - Rundek, Tatjana

PY - 2012/9/1

Y1 - 2012/9/1

N2 - Carotid intima-media thickness (cIMT) and carotid plaque are ultrasound imaging measures of carotid atherosclerosis and strong predictors of future stroke, myocardial infarction and vascular death. The use of ultrasound measures of cIMT and carotid plaque as a screening tool in clinical practice however have been extremely limited by a lack of recognition of its value by medical communities, health care policy makers and a lack of reimbursement by thirdparty payers engaged in the delivery of vascular imaging services. This review addresses the role of cIMT and plaque in vascular disease risk prediction. Recent data from large population based studies on reclassification of the vascular risk using carotid ultrasound imaging markers is presented. In addition, the common clinical scenarios for the appropriate use of cIMT in clinical setting are summarized according to the recent study conducted by the Society of the Atherosclerosis Imaging and Prevention in collaboration with the International Atherosclerosis Society. This presentation is intended to provide a practical guide for use of cIMT and plaque to clinicians to promote optimal clinical use of cIMT and to researchers to direct cIMT and plaque research towards investigating environmental and genetic factors of a complex disorder - subclinical atherosclerosis - leading to future genetic discoveries and new anti-Atherosclerotic therapies.

AB - Carotid intima-media thickness (cIMT) and carotid plaque are ultrasound imaging measures of carotid atherosclerosis and strong predictors of future stroke, myocardial infarction and vascular death. The use of ultrasound measures of cIMT and carotid plaque as a screening tool in clinical practice however have been extremely limited by a lack of recognition of its value by medical communities, health care policy makers and a lack of reimbursement by thirdparty payers engaged in the delivery of vascular imaging services. This review addresses the role of cIMT and plaque in vascular disease risk prediction. Recent data from large population based studies on reclassification of the vascular risk using carotid ultrasound imaging markers is presented. In addition, the common clinical scenarios for the appropriate use of cIMT in clinical setting are summarized according to the recent study conducted by the Society of the Atherosclerosis Imaging and Prevention in collaboration with the International Atherosclerosis Society. This presentation is intended to provide a practical guide for use of cIMT and plaque to clinicians to promote optimal clinical use of cIMT and to researchers to direct cIMT and plaque research towards investigating environmental and genetic factors of a complex disorder - subclinical atherosclerosis - leading to future genetic discoveries and new anti-Atherosclerotic therapies.

KW - Carotid artery

KW - Carotid IMT

KW - Plaque

KW - Risk factors

KW - Surrogate markers

KW - Ultrasound

UR - http://www.scopus.com/inward/record.url?scp=84867576329&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84867576329&partnerID=8YFLogxK

U2 - 10.1016/j.permed.2012.01.006

DO - 10.1016/j.permed.2012.01.006

M3 - Article

AN - SCOPUS:84867576329

VL - 1-12

SP - 139

EP - 145

JO - Perspectives in Medicine

JF - Perspectives in Medicine

SN - 2211-968X

ER -