Cardiovascular risk factors and myocardial infarction in patients with psoriasis

Michael Shelling, Srdjan Prodanovich, Robert Kirsner

Research output: Contribution to journalArticle

Abstract

Evaluation of: Gelfand JM, Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB. Risk of myocardial infarction in patients with psoriasis. JAMA 296(14), 1735–1741 (2006). Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB, Gelfand JM. Prevalence of cardiovascular risk factors in patients with psoriasis. J. Am. Acad. Dermatol. 55(5), 829–835 (2006). Psoriasis is a chronic disease characterized by systemic inflammation and inappropriate self-reactivity of the T helper cell (Th)1-mediated immune system. It is well known that, for patients, psoriasis has a significant impact on the quality of life, but recent data also suggest that psoriasis produces significant morbidity and possibly even mortality related to associated cardiovascular effects. We review two recent papers, which provide analysis of cardiovascular risk factors and myocardial infarction rates in patients with mild and severe psoriasis in a large-scale population-based study in the UK. These investigators use multivariate analysis to determine the true independent associations of these risk factors with psoriasis and to examine psoriasis as an independent risk factor for myocardial infarction.

Original languageEnglish (US)
Pages (from-to)19-23
Number of pages5
JournalExpert Review of Dermatology
Volume2
Issue number1
DOIs
StatePublished - Feb 1 2007

Fingerprint

Psoriasis
Myocardial Infarction
Th1 Cells
Immune System
Chronic Disease
Multivariate Analysis
Quality of Life
Research Personnel
Inflammation
Morbidity
Mortality
Population

Keywords

  • cardiovascular risk
  • heart disease
  • myocardial infarction
  • psoriasis
  • systemic inflammation

ASJC Scopus subject areas

  • Dermatology

Cite this

Cardiovascular risk factors and myocardial infarction in patients with psoriasis. / Shelling, Michael; Prodanovich, Srdjan; Kirsner, Robert.

In: Expert Review of Dermatology, Vol. 2, No. 1, 01.02.2007, p. 19-23.

Research output: Contribution to journalArticle

@article{bb659e7e413b4ed79e2c4cbc84b9e4a6,
title = "Cardiovascular risk factors and myocardial infarction in patients with psoriasis",
abstract = "Evaluation of: Gelfand JM, Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB. Risk of myocardial infarction in patients with psoriasis. JAMA 296(14), 1735–1741 (2006). Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB, Gelfand JM. Prevalence of cardiovascular risk factors in patients with psoriasis. J. Am. Acad. Dermatol. 55(5), 829–835 (2006). Psoriasis is a chronic disease characterized by systemic inflammation and inappropriate self-reactivity of the T helper cell (Th)1-mediated immune system. It is well known that, for patients, psoriasis has a significant impact on the quality of life, but recent data also suggest that psoriasis produces significant morbidity and possibly even mortality related to associated cardiovascular effects. We review two recent papers, which provide analysis of cardiovascular risk factors and myocardial infarction rates in patients with mild and severe psoriasis in a large-scale population-based study in the UK. These investigators use multivariate analysis to determine the true independent associations of these risk factors with psoriasis and to examine psoriasis as an independent risk factor for myocardial infarction.",
keywords = "cardiovascular risk, heart disease, myocardial infarction, psoriasis, systemic inflammation",
author = "Michael Shelling and Srdjan Prodanovich and Robert Kirsner",
year = "2007",
month = "2",
day = "1",
doi = "10.1586/17469872.2.1.19",
language = "English (US)",
volume = "2",
pages = "19--23",
journal = "Expert Review of Dermatology",
issn = "1746-9872",
publisher = "Expert Reviews Ltd.",
number = "1",

}

TY - JOUR

T1 - Cardiovascular risk factors and myocardial infarction in patients with psoriasis

AU - Shelling, Michael

AU - Prodanovich, Srdjan

AU - Kirsner, Robert

PY - 2007/2/1

Y1 - 2007/2/1

N2 - Evaluation of: Gelfand JM, Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB. Risk of myocardial infarction in patients with psoriasis. JAMA 296(14), 1735–1741 (2006). Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB, Gelfand JM. Prevalence of cardiovascular risk factors in patients with psoriasis. J. Am. Acad. Dermatol. 55(5), 829–835 (2006). Psoriasis is a chronic disease characterized by systemic inflammation and inappropriate self-reactivity of the T helper cell (Th)1-mediated immune system. It is well known that, for patients, psoriasis has a significant impact on the quality of life, but recent data also suggest that psoriasis produces significant morbidity and possibly even mortality related to associated cardiovascular effects. We review two recent papers, which provide analysis of cardiovascular risk factors and myocardial infarction rates in patients with mild and severe psoriasis in a large-scale population-based study in the UK. These investigators use multivariate analysis to determine the true independent associations of these risk factors with psoriasis and to examine psoriasis as an independent risk factor for myocardial infarction.

AB - Evaluation of: Gelfand JM, Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB. Risk of myocardial infarction in patients with psoriasis. JAMA 296(14), 1735–1741 (2006). Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB, Gelfand JM. Prevalence of cardiovascular risk factors in patients with psoriasis. J. Am. Acad. Dermatol. 55(5), 829–835 (2006). Psoriasis is a chronic disease characterized by systemic inflammation and inappropriate self-reactivity of the T helper cell (Th)1-mediated immune system. It is well known that, for patients, psoriasis has a significant impact on the quality of life, but recent data also suggest that psoriasis produces significant morbidity and possibly even mortality related to associated cardiovascular effects. We review two recent papers, which provide analysis of cardiovascular risk factors and myocardial infarction rates in patients with mild and severe psoriasis in a large-scale population-based study in the UK. These investigators use multivariate analysis to determine the true independent associations of these risk factors with psoriasis and to examine psoriasis as an independent risk factor for myocardial infarction.

KW - cardiovascular risk

KW - heart disease

KW - myocardial infarction

KW - psoriasis

KW - systemic inflammation

UR - http://www.scopus.com/inward/record.url?scp=85018899787&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85018899787&partnerID=8YFLogxK

U2 - 10.1586/17469872.2.1.19

DO - 10.1586/17469872.2.1.19

M3 - Article

AN - SCOPUS:85018899787

VL - 2

SP - 19

EP - 23

JO - Expert Review of Dermatology

JF - Expert Review of Dermatology

SN - 1746-9872

IS - 1

ER -