Cardiovascular risk factors and myocardial infarction in patients with psoriasis

Michael Shelling, Srdjan Prodanovich, Robert Kirsner

Research output: Contribution to journalArticlepeer-review

Abstract

Evaluation of: Gelfand JM, Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB. Risk of myocardial infarction in patients with psoriasis. JAMA 296(14), 1735–1741 (2006). Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB, Gelfand JM. Prevalence of cardiovascular risk factors in patients with psoriasis. J. Am. Acad. Dermatol. 55(5), 829–835 (2006). Psoriasis is a chronic disease characterized by systemic inflammation and inappropriate self-reactivity of the T helper cell (Th)1-mediated immune system. It is well known that, for patients, psoriasis has a significant impact on the quality of life, but recent data also suggest that psoriasis produces significant morbidity and possibly even mortality related to associated cardiovascular effects. We review two recent papers, which provide analysis of cardiovascular risk factors and myocardial infarction rates in patients with mild and severe psoriasis in a large-scale population-based study in the UK. These investigators use multivariate analysis to determine the true independent associations of these risk factors with psoriasis and to examine psoriasis as an independent risk factor for myocardial infarction.

Original languageEnglish (US)
Pages (from-to)19-23
Number of pages5
JournalExpert Review of Dermatology
Volume2
Issue number1
DOIs
StatePublished - Feb 1 2007

Keywords

  • cardiovascular risk
  • heart disease
  • myocardial infarction
  • psoriasis
  • systemic inflammation

ASJC Scopus subject areas

  • Dermatology

Fingerprint Dive into the research topics of 'Cardiovascular risk factors and myocardial infarction in patients with psoriasis'. Together they form a unique fingerprint.

Cite this