Cardiovascular effects of glucagon in man

Joseph W. Linhart, S. Serge Barold, Lawrence S. Cohen, Frank J. Hildner, Philip Samet

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Cardiovascular effects of an intravenous injection of glucagon, 3 mg., were studied in 8 subjects during cardiac catheterization. In each study a prompt effect was noted, with an increase in heart rate, cardiac output, right ventricular dp/dt and right ventricular and systemic systolic pressures. Right ventricular end-diastolic pressure and systemic vascular resistance decreased. It is concluded that glucagon exerts positive inotropic and chronotropic effects upon the heart in man. Further studies are required to determine its proper clinical role and mechanism of action.

Original languageEnglish
Pages (from-to)706-710
Number of pages5
JournalThe American journal of cardiology
Volume22
Issue number5
StatePublished - Nov 1 1968
Externally publishedYes

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Glucagon
Blood Pressure
Cardiac Catheterization
Intravenous Injections
Cardiac Output
Vascular Resistance
Heart Rate

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Linhart, J. W., Barold, S. S., Cohen, L. S., Hildner, F. J., & Samet, P. (1968). Cardiovascular effects of glucagon in man. The American journal of cardiology, 22(5), 706-710.

Cardiovascular effects of glucagon in man. / Linhart, Joseph W.; Barold, S. Serge; Cohen, Lawrence S.; Hildner, Frank J.; Samet, Philip.

In: The American journal of cardiology, Vol. 22, No. 5, 01.11.1968, p. 706-710.

Research output: Contribution to journalArticle

Linhart, JW, Barold, SS, Cohen, LS, Hildner, FJ & Samet, P 1968, 'Cardiovascular effects of glucagon in man', The American journal of cardiology, vol. 22, no. 5, pp. 706-710.
Linhart JW, Barold SS, Cohen LS, Hildner FJ, Samet P. Cardiovascular effects of glucagon in man. The American journal of cardiology. 1968 Nov 1;22(5):706-710.
Linhart, Joseph W. ; Barold, S. Serge ; Cohen, Lawrence S. ; Hildner, Frank J. ; Samet, Philip. / Cardiovascular effects of glucagon in man. In: The American journal of cardiology. 1968 ; Vol. 22, No. 5. pp. 706-710.
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