Cardiovascular dynamics and adrenergic responses of the rainbow trout in vivo.

C. M. Wood, G. Shelton

Research output: Contribution to journalArticle

87 Citations (Scopus)

Abstract

Cardiac output and dorsal aorta, ventral aorta, caudal artery, caudal vein, and subintestinal vein pressures have been directly measured in intact unanaesthetized trout. Cardiac output (Q) averaged 36.7 ml/kg.min. The pressure drop across the systemic vascular resistance (Rs) was approximately twice that across the gill resistance (Rg), and a significant positive pressure persisted in the venous system. alpha-Adrenergic blockade revealed a considerable endogenous vasomotor tone resulting from latent adrenergic constriction of Rs. Intravenous adrenaline caused a pressor response throughout the circulatory system which has been analysed in detail with the aid of previous studies on isolated parts of the trout circulation. The complex and variable form of the pressor response reflected differential contributions from changes in Q, Rg, and Rs. Increases in Rs (alpha-receptor activation) were the principal cause of all pressor responses. Rg usually declined slightly due to passive dilation and/or beta-receptor stimulation, but occasionally increased due to alpha-receptor activation. The cardiac response reflected a varying balance between a direct beta-stimulatory effect of adrenaline on Q and an indirect passive inhibition of Q by the increase in peripheral resistance. Both effects were mediated through changes in stroke volume. Occasional tachycardia or more frequent reflex bradycardia were minor components of the cardiac response. The in vivo actions of other adrenergic agents have been similarly analysed.

Original languageEnglish
Pages (from-to)247-270
Number of pages24
JournalJournal of Experimental Biology
Volume87
StatePublished - Aug 1 1980

Fingerprint

Oncorhynchus mykiss
Adrenergic Agents
rainbow
Trout
epinephrine
cardiac output
aorta
Pressure
cardiovascular system
Cardiac Output
Vascular Resistance
trout
receptors
Epinephrine
Aorta
Veins
dilation
adrenergic agents
pressure drop
circulatory system

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Agricultural and Biological Sciences (miscellaneous)

Cite this

Cardiovascular dynamics and adrenergic responses of the rainbow trout in vivo. / Wood, C. M.; Shelton, G.

In: Journal of Experimental Biology, Vol. 87, 01.08.1980, p. 247-270.

Research output: Contribution to journalArticle

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