Cardiovascular complications of HIV infection in children

S. Kaplan, Steven E Lipshultz

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The cardiovascular system is frequently involved in children infected with the human immunodeficiency virus (HIV). The clinical picture, however, may be dominated by intercurrent infections, hepatosplenomegaly, interstitial lung disease, malnutrition, and anemia; thus, the cardiovascular involvement may be occult. Early diagnosis of cardiovascular disease permits prompt intervention, which delays and possibly prevents complications such as progressive left ventricular dysfunction. Therefore, routine serial monitoring of left ventricular function with echocardiography is advised in HIV-ifected children, allowing early identification and successful treatment of many patients with heart failure in whom the clinical picture may be erroneously attributed solely to pulmonary disease or intercurrent infection. Identification of the mechanism of arrhythmias caused by myocarditis, inflammation of the conduction system, electrolye abnormalities, and complications from drug therapy (eg, prolonged QT(c) from pentamidine therapy) allows institution of prompt therapy and possible prevention of cardiorespiratory arrest.

Original languageEnglish
Pages (from-to)99-105
Number of pages7
JournalCardiology in Review
Volume3
Issue number2
StatePublished - Jan 1 1995
Externally publishedYes

Fingerprint

Virus Diseases
HIV
Pentamidine
Interstitial Lung Diseases
Myocarditis
Left Ventricular Dysfunction
Cardiovascular System
Infection
Left Ventricular Function
Malnutrition
Lung Diseases
Echocardiography
Cardiac Arrhythmias
Anemia
Early Diagnosis
Cardiovascular Diseases
Therapeutics
Heart Failure
Inflammation
Drug Therapy

Keywords

  • acquired immune deficiency syndrome
  • AIDS
  • cardiomyopathy
  • cardiorespiratory arrest
  • HIV
  • human immunodeficiency virus
  • left ventricular dysfunction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Kaplan, S., & Lipshultz, S. E. (1995). Cardiovascular complications of HIV infection in children. Cardiology in Review, 3(2), 99-105.

Cardiovascular complications of HIV infection in children. / Kaplan, S.; Lipshultz, Steven E.

In: Cardiology in Review, Vol. 3, No. 2, 01.01.1995, p. 99-105.

Research output: Contribution to journalArticle

Kaplan, S & Lipshultz, SE 1995, 'Cardiovascular complications of HIV infection in children', Cardiology in Review, vol. 3, no. 2, pp. 99-105.
Kaplan, S. ; Lipshultz, Steven E. / Cardiovascular complications of HIV infection in children. In: Cardiology in Review. 1995 ; Vol. 3, No. 2. pp. 99-105.
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