Abstract
Astemizole, a nonsedating antihistamine, caused a prolonged corrected QT interval, ventricular dysrhythmias, and atrioventricular heart block after overdose in five children. Cardiotoxic effects lasted an averaged of 2 1/2 days. Children poisoned with astemizole need emergent medical evaluation, a 12-lead electro-cardiogram with calculation of the corrected QT interval, and continuous cardiac monitoring for 24 hours.
Original language | English (US) |
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Pages (from-to) | 799-802 |
Number of pages | 4 |
Journal | The Journal of Pediatrics |
Volume | 120 |
Issue number | 5 |
DOIs | |
State | Published - May 1992 |
Externally published | Yes |
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health